The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trial
Abstract Mobile health (mHealth) tools can be used to deliver nonpharmacologic therapies to patients with migraine. However, mHealth studies often report poor treatment adherence. Neuroscience Education Therapy (NET), behavioral economics, and Digital Navigators have the potential to increase treatm...
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| Format: | Article |
| Language: | English |
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Springer
2025-01-01
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| Series: | NPP-Digital Psychiatry and Neuroscience |
| Online Access: | https://doi.org/10.1038/s44277-024-00021-w |
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| author | Mia T. Minen Erin K. Waire John Torous Jessica Fishman Richard B. Lipton Scott W. Powers |
| author_facet | Mia T. Minen Erin K. Waire John Torous Jessica Fishman Richard B. Lipton Scott W. Powers |
| author_sort | Mia T. Minen |
| collection | DOAJ |
| description | Abstract Mobile health (mHealth) tools can be used to deliver nonpharmacologic therapies to patients with migraine. However, mHealth studies often report poor treatment adherence. Neuroscience Education Therapy (NET), behavioral economics, and Digital Navigators have the potential to increase treatment adherence and thereby improve remote migraine self-management. We conducted a 6-month prospective pilot randomized controlled trial testing if a multi-component package of behavioral interventions increased treatment adherence among patients using one of two different mHealth migraine self-management programs (low-intensity program consisting only of a headache diary versus high-intensity program consisting of a headache diary and behavioral exercises). Our outcomes were the number of diary entries and behavioral exercises completed/week captured via back-end analytics of the mHealth application. We also compared our adherence data at 90-days (a secondary endpoint to assess the durability of the effect) with adherence data from similar published studies without the adherence-enhancing package. We enrolled 26 participants (n = 15 low intensity group, n = 11 high-intensity group). During the 6-week intervention period, we had a median of 7 headache diary entries/week in both groups and a median of 6 days/week of behavioral exercises in the high-intensity group. The rate of adherence with the adherence-enhancing package included was 2.9-8x higher compared to the median rates of the behavioral exercises to historical controls. With use of NET, behavioral economics, and digital navigators, participants achieved higher levels of adherence to both self-management programs compared to prior remote migraine self-management studies. Therefore, these tools may be beneficial to improving adherence to migraine self-management programs. |
| format | Article |
| id | doaj-art-bb5a2b8e324443f78eb650260517c752 |
| institution | Kabale University |
| issn | 2948-1570 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Springer |
| record_format | Article |
| series | NPP-Digital Psychiatry and Neuroscience |
| spelling | doaj-art-bb5a2b8e324443f78eb650260517c7522025-01-26T12:36:55ZengSpringerNPP-Digital Psychiatry and Neuroscience2948-15702025-01-01311810.1038/s44277-024-00021-wThe impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trialMia T. Minen0Erin K. Waire1John Torous2Jessica Fishman3Richard B. Lipton4Scott W. Powers5Departments of Neurology and Population Health, NYU Langone HealthDepartment of Neurology, NYU Langone HealthDepartment of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical SchoolMessage Effects Lab, University of PennsylvaniaDepartment of Neurology, Albert Einstein College of MedicineDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH; Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children’s HospitalAbstract Mobile health (mHealth) tools can be used to deliver nonpharmacologic therapies to patients with migraine. However, mHealth studies often report poor treatment adherence. Neuroscience Education Therapy (NET), behavioral economics, and Digital Navigators have the potential to increase treatment adherence and thereby improve remote migraine self-management. We conducted a 6-month prospective pilot randomized controlled trial testing if a multi-component package of behavioral interventions increased treatment adherence among patients using one of two different mHealth migraine self-management programs (low-intensity program consisting only of a headache diary versus high-intensity program consisting of a headache diary and behavioral exercises). Our outcomes were the number of diary entries and behavioral exercises completed/week captured via back-end analytics of the mHealth application. We also compared our adherence data at 90-days (a secondary endpoint to assess the durability of the effect) with adherence data from similar published studies without the adherence-enhancing package. We enrolled 26 participants (n = 15 low intensity group, n = 11 high-intensity group). During the 6-week intervention period, we had a median of 7 headache diary entries/week in both groups and a median of 6 days/week of behavioral exercises in the high-intensity group. The rate of adherence with the adherence-enhancing package included was 2.9-8x higher compared to the median rates of the behavioral exercises to historical controls. With use of NET, behavioral economics, and digital navigators, participants achieved higher levels of adherence to both self-management programs compared to prior remote migraine self-management studies. Therefore, these tools may be beneficial to improving adherence to migraine self-management programs.https://doi.org/10.1038/s44277-024-00021-w |
| spellingShingle | Mia T. Minen Erin K. Waire John Torous Jessica Fishman Richard B. Lipton Scott W. Powers The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trial NPP-Digital Psychiatry and Neuroscience |
| title | The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trial |
| title_full | The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trial |
| title_fullStr | The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trial |
| title_full_unstemmed | The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trial |
| title_short | The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trial |
| title_sort | impact of neuroscience education therapy behavioral economics and digital navigators on patient migraine treatment adherence to a mobile health application a prospective pilot randomized controlled trial |
| url | https://doi.org/10.1038/s44277-024-00021-w |
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