Pleural Effusion: A Rare Side Effect of Nilotinib—A Case Report
Pleural effusion, as a side effect of tyrosine kinases, may be seen as most commonly associated with dasatinib and very rarely seen with nilotinib. In this report we present a chronic phase of CML case that was treated with nilotinib due to imatinib (Gleevec) allergy and had pleural effusion with ni...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/203939 |
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| author | Hava Üsküdar Teke Olga Meltem Akay Deniz Gören Şahin Mustafa Karagülle Eren Gündüz Neslihan Andıç |
| author_facet | Hava Üsküdar Teke Olga Meltem Akay Deniz Gören Şahin Mustafa Karagülle Eren Gündüz Neslihan Andıç |
| author_sort | Hava Üsküdar Teke |
| collection | DOAJ |
| description | Pleural effusion, as a side effect of tyrosine kinases, may be seen as most commonly associated with dasatinib and very rarely seen with nilotinib. In this report we present a chronic phase of CML case that was treated with nilotinib due to imatinib (Gleevec) allergy and had pleural effusion with nilotinib at 5th year of treatment. If pleural effusion develops in patients taking nilotinib and if this effusion is exudative and lymphocyte predominant, after ruling out pulmonary and cardiac etiologies, it must be associated with nilotinib; according to stage of effusion drug should be discontinued and/or steroid should be started and/or surgery should be performed. |
| format | Article |
| id | doaj-art-bb537bde4c31452fa00b7054a4ef669c |
| institution | DOAJ |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-bb537bde4c31452fa00b7054a4ef669c2025-08-20T03:22:53ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/203939203939Pleural Effusion: A Rare Side Effect of Nilotinib—A Case ReportHava Üsküdar Teke0Olga Meltem Akay1Deniz Gören Şahin2Mustafa Karagülle3Eren Gündüz4Neslihan Andıç5Hematology, Medical Faculty, Eskişehir Osmangazi University, 26090 Eskişehir, TurkeyHematology, Medical Faculty, Eskişehir Osmangazi University, 26090 Eskişehir, TurkeyHematology, Medical Faculty, Eskişehir Osmangazi University, 26090 Eskişehir, TurkeyHematology, Medical Faculty, Eskişehir Osmangazi University, 26090 Eskişehir, TurkeyHematology, Medical Faculty, Eskişehir Osmangazi University, 26090 Eskişehir, TurkeyHematology, Medical Faculty, Eskişehir Osmangazi University, 26090 Eskişehir, TurkeyPleural effusion, as a side effect of tyrosine kinases, may be seen as most commonly associated with dasatinib and very rarely seen with nilotinib. In this report we present a chronic phase of CML case that was treated with nilotinib due to imatinib (Gleevec) allergy and had pleural effusion with nilotinib at 5th year of treatment. If pleural effusion develops in patients taking nilotinib and if this effusion is exudative and lymphocyte predominant, after ruling out pulmonary and cardiac etiologies, it must be associated with nilotinib; according to stage of effusion drug should be discontinued and/or steroid should be started and/or surgery should be performed.http://dx.doi.org/10.1155/2014/203939 |
| spellingShingle | Hava Üsküdar Teke Olga Meltem Akay Deniz Gören Şahin Mustafa Karagülle Eren Gündüz Neslihan Andıç Pleural Effusion: A Rare Side Effect of Nilotinib—A Case Report Case Reports in Medicine |
| title | Pleural Effusion: A Rare Side Effect of Nilotinib—A Case Report |
| title_full | Pleural Effusion: A Rare Side Effect of Nilotinib—A Case Report |
| title_fullStr | Pleural Effusion: A Rare Side Effect of Nilotinib—A Case Report |
| title_full_unstemmed | Pleural Effusion: A Rare Side Effect of Nilotinib—A Case Report |
| title_short | Pleural Effusion: A Rare Side Effect of Nilotinib—A Case Report |
| title_sort | pleural effusion a rare side effect of nilotinib a case report |
| url | http://dx.doi.org/10.1155/2014/203939 |
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