Complications leading to hospitalisation 12 months after brachytherapy or high-intensity focused ultrasound for localized prostate cancer: French national from the PMSI-MCO data, 2019 and 2020
Background and purpose: Prostate cancer can be treated using either brachytherapy or high-intensity focused ultrasound (HIFU), which are less invasive than surgery. Although both approaches have proved effective, few studies have looked at the specific causes of hospitalisation due to complications,...
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| Format: | Article |
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Elsevier
2024-11-01
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| Series: | Clinical and Translational Radiation Oncology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405630824001319 |
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| author | Timothée Bourgarit Clément Larose Andrea Dagry Nicolas Martz Beverley Balkau Pascal Eschwège Charles Mazeaud |
| author_facet | Timothée Bourgarit Clément Larose Andrea Dagry Nicolas Martz Beverley Balkau Pascal Eschwège Charles Mazeaud |
| author_sort | Timothée Bourgarit |
| collection | DOAJ |
| description | Background and purpose: Prostate cancer can be treated using either brachytherapy or high-intensity focused ultrasound (HIFU), which are less invasive than surgery. Although both approaches have proved effective, few studies have looked at the specific causes of hospitalisation due to complications, following these treatments. The aim of this study was to compare the causes of hospitalisation. Methods: A retrospective study was carried out examining the records of patients who had undergone brachytherapy or HIFU treatment for localized prostate cancer in 2019 and 2020, using the French national database: Programme de Médicalisation du Système d’Information − Médecine, Chirurgie, Obstétrique (PMSI-MSO). Data on post-treatment hospitalisations were analyzed. Results: 3090 patients were included in the study, of whom 1699 underwent brachytherapy and 1391 HIFU procedures. The incidence of hospitalisation was much higher after HIFU than after brachytherapy, notably due to a higher rate of obstructive complications (12.94% vs 2.77%). Large differences were also found for infections (8.20% vs 1.47%) and bleeding (6.76% vs 2.18%) leading to hospitalisation. Most of the complications occurred at the initial hospitalization: 12% for HIFU, and 1.4% for brachytherapy. Conclusion: Complications were more frequent after treatment with HIFU than with brachytherapy in the year following treatment for localized prostate cancer. Further the causes of hospitalisation differed between the two treatments. These differences need to be taken into account in the therapeutic strategy, as well as in post-treatment management. |
| format | Article |
| id | doaj-art-bb4cecb826ae477fa7ef6ecd45a8727b |
| institution | OA Journals |
| issn | 2405-6308 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical and Translational Radiation Oncology |
| spelling | doaj-art-bb4cecb826ae477fa7ef6ecd45a8727b2025-08-20T02:18:20ZengElsevierClinical and Translational Radiation Oncology2405-63082024-11-014910085410.1016/j.ctro.2024.100854Complications leading to hospitalisation 12 months after brachytherapy or high-intensity focused ultrasound for localized prostate cancer: French national from the PMSI-MCO data, 2019 and 2020Timothée Bourgarit0Clément Larose1Andrea Dagry2Nicolas Martz3Beverley Balkau4Pascal Eschwège5Charles Mazeaud6Department of Urology CHRU Nancy, Brabois Hospital, 54000 Nancy, France; Corresponding author.Department of Urology CHRU Nancy, Brabois Hospital, 54000 Nancy, FranceReal Consulting Data, 92120 Montrouge, FranceRadiation Department, Lorraine Cancer Institute, 54000 Nancy, FranceINSERM U1018, Clinical Epidemiology, CESP, 94807 Villejuif, FranceDepartment of Urology CHRU Nancy, Brabois Hospital, 54000 Nancy, France; CNRS UMR 7039, Tumor Biology Unit, CRAN, 54547 Vandœuvre-lès-Nancy, FranceDepartment of Urology CHRU Nancy, Brabois Hospital, 54000 Nancy, France; Université de Lorraine, Inserm, IADI U1254, 54000 Nancy, FranceBackground and purpose: Prostate cancer can be treated using either brachytherapy or high-intensity focused ultrasound (HIFU), which are less invasive than surgery. Although both approaches have proved effective, few studies have looked at the specific causes of hospitalisation due to complications, following these treatments. The aim of this study was to compare the causes of hospitalisation. Methods: A retrospective study was carried out examining the records of patients who had undergone brachytherapy or HIFU treatment for localized prostate cancer in 2019 and 2020, using the French national database: Programme de Médicalisation du Système d’Information − Médecine, Chirurgie, Obstétrique (PMSI-MSO). Data on post-treatment hospitalisations were analyzed. Results: 3090 patients were included in the study, of whom 1699 underwent brachytherapy and 1391 HIFU procedures. The incidence of hospitalisation was much higher after HIFU than after brachytherapy, notably due to a higher rate of obstructive complications (12.94% vs 2.77%). Large differences were also found for infections (8.20% vs 1.47%) and bleeding (6.76% vs 2.18%) leading to hospitalisation. Most of the complications occurred at the initial hospitalization: 12% for HIFU, and 1.4% for brachytherapy. Conclusion: Complications were more frequent after treatment with HIFU than with brachytherapy in the year following treatment for localized prostate cancer. Further the causes of hospitalisation differed between the two treatments. These differences need to be taken into account in the therapeutic strategy, as well as in post-treatment management.http://www.sciencedirect.com/science/article/pii/S2405630824001319BrachytherapyComplicationsHIFULocalized prostate cancer |
| spellingShingle | Timothée Bourgarit Clément Larose Andrea Dagry Nicolas Martz Beverley Balkau Pascal Eschwège Charles Mazeaud Complications leading to hospitalisation 12 months after brachytherapy or high-intensity focused ultrasound for localized prostate cancer: French national from the PMSI-MCO data, 2019 and 2020 Clinical and Translational Radiation Oncology Brachytherapy Complications HIFU Localized prostate cancer |
| title | Complications leading to hospitalisation 12 months after brachytherapy or high-intensity focused ultrasound for localized prostate cancer: French national from the PMSI-MCO data, 2019 and 2020 |
| title_full | Complications leading to hospitalisation 12 months after brachytherapy or high-intensity focused ultrasound for localized prostate cancer: French national from the PMSI-MCO data, 2019 and 2020 |
| title_fullStr | Complications leading to hospitalisation 12 months after brachytherapy or high-intensity focused ultrasound for localized prostate cancer: French national from the PMSI-MCO data, 2019 and 2020 |
| title_full_unstemmed | Complications leading to hospitalisation 12 months after brachytherapy or high-intensity focused ultrasound for localized prostate cancer: French national from the PMSI-MCO data, 2019 and 2020 |
| title_short | Complications leading to hospitalisation 12 months after brachytherapy or high-intensity focused ultrasound for localized prostate cancer: French national from the PMSI-MCO data, 2019 and 2020 |
| title_sort | complications leading to hospitalisation 12 months after brachytherapy or high intensity focused ultrasound for localized prostate cancer french national from the pmsi mco data 2019 and 2020 |
| topic | Brachytherapy Complications HIFU Localized prostate cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2405630824001319 |
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