ISH-guided freeze-matrix assisted punches: technique for extracting punches from thin slide-mounted tissues for DNA methylation analysis

Dissection of discrete brain regions for molecular analysis is complicated by trade-offs between accuracy, flexibility, and costs. We developed a flexible and cost-effective method, in situ hybridization (ISH) guided freeze-matrix assisted punches (IFAP), for extracting nanogram quantities of DNA fr...

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Bibliographic Details
Main Authors: Lawrence S. Own, Paresh D. Patel
Format: Article
Language:English
Published: Taylor & Francis Group 2012-09-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/0000113912
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