Angiotensin (1–7) Improves Pancreatic Islet Function via Upregulating PDX-1 and GCK: A Dose-Dependent Study in Mice
Conclusion: Angiotensin (1–7) could improve glucose and lipid metabolism and islet function by promoting the expression of PDX-1 and GCK genes in the pancreas of db/db mice.
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/ije/1672096 |
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| _version_ | 1850041530277953536 |
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| author | Ziwei Lin Jiaqi Lin Anqi Huang Zixu Zhang Xinyi Wu Guoshu Yin Chiju Wei Wencan Xu |
| author_facet | Ziwei Lin Jiaqi Lin Anqi Huang Zixu Zhang Xinyi Wu Guoshu Yin Chiju Wei Wencan Xu |
| author_sort | Ziwei Lin |
| collection | DOAJ |
| description | Conclusion: Angiotensin (1–7) could improve glucose and lipid metabolism and islet function by promoting the expression of PDX-1 and GCK genes in the pancreas of db/db mice. |
| format | Article |
| id | doaj-art-bb461f260bad4b5bb26e23946c737537 |
| institution | DOAJ |
| issn | 1687-8345 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-bb461f260bad4b5bb26e23946c7375372025-08-20T02:55:45ZengWileyInternational Journal of Endocrinology1687-83452024-01-01202410.1155/ije/1672096Angiotensin (1–7) Improves Pancreatic Islet Function via Upregulating PDX-1 and GCK: A Dose-Dependent Study in MiceZiwei Lin0Jiaqi Lin1Anqi Huang2Zixu Zhang3Xinyi Wu4Guoshu Yin5Chiju Wei6Wencan Xu7Shantou University Medical CollegeShantou University Medical CollegeShantou University Medical CollegeShantou University Medical CollegeShantou University Medical CollegeDepartment of Endocrinology and MetabolismMultidisciplinary Research CenterDepartment of Endocrinology and MetabolismConclusion: Angiotensin (1–7) could improve glucose and lipid metabolism and islet function by promoting the expression of PDX-1 and GCK genes in the pancreas of db/db mice.http://dx.doi.org/10.1155/ije/1672096 |
| spellingShingle | Ziwei Lin Jiaqi Lin Anqi Huang Zixu Zhang Xinyi Wu Guoshu Yin Chiju Wei Wencan Xu Angiotensin (1–7) Improves Pancreatic Islet Function via Upregulating PDX-1 and GCK: A Dose-Dependent Study in Mice International Journal of Endocrinology |
| title | Angiotensin (1–7) Improves Pancreatic Islet Function via Upregulating PDX-1 and GCK: A Dose-Dependent Study in Mice |
| title_full | Angiotensin (1–7) Improves Pancreatic Islet Function via Upregulating PDX-1 and GCK: A Dose-Dependent Study in Mice |
| title_fullStr | Angiotensin (1–7) Improves Pancreatic Islet Function via Upregulating PDX-1 and GCK: A Dose-Dependent Study in Mice |
| title_full_unstemmed | Angiotensin (1–7) Improves Pancreatic Islet Function via Upregulating PDX-1 and GCK: A Dose-Dependent Study in Mice |
| title_short | Angiotensin (1–7) Improves Pancreatic Islet Function via Upregulating PDX-1 and GCK: A Dose-Dependent Study in Mice |
| title_sort | angiotensin 1 7 improves pancreatic islet function via upregulating pdx 1 and gck a dose dependent study in mice |
| url | http://dx.doi.org/10.1155/ije/1672096 |
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