Symptomatic Liver Cyst Successfully Treated with Transgastric Drainage and Sclerotherapy Using Minocycline Hydrochloride

A liver cyst is hepatic fluid-filled cavities often detected in clinical surveillances such as a health examination. Although the liver cyst is usually asymptomatic and observed without any therapeutic intervention, it can be symptomatic and needs treatment due to its enlargement, hemorrhage, and in...

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Main Authors: Kengo Yoshitomi, Yudai Koya, Koichiro Miyagawa, Yuki Maruno, Koki Yamaguchi, Ryuta Taniguchi, Koji Onitsuka, Yoshitaka Sakamoto, Shinji Oe, Masaru Harada
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2024/6942345
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author Kengo Yoshitomi
Yudai Koya
Koichiro Miyagawa
Yuki Maruno
Koki Yamaguchi
Ryuta Taniguchi
Koji Onitsuka
Yoshitaka Sakamoto
Shinji Oe
Masaru Harada
author_facet Kengo Yoshitomi
Yudai Koya
Koichiro Miyagawa
Yuki Maruno
Koki Yamaguchi
Ryuta Taniguchi
Koji Onitsuka
Yoshitaka Sakamoto
Shinji Oe
Masaru Harada
author_sort Kengo Yoshitomi
collection DOAJ
description A liver cyst is hepatic fluid-filled cavities often detected in clinical surveillances such as a health examination. Although the liver cyst is usually asymptomatic and observed without any therapeutic intervention, it can be symptomatic and needs treatment due to its enlargement, hemorrhage, and infection. A 74-year-old woman presented with upper abdominal pain and a huge liver cyst in the left lobe. Several examinations including image findings revealed that the symptom could be derived from the liver cyst. Although there is no definite guideline of treatment for symptomatic liver cysts, percutaneous ultrasound-guided drainage with sclerotherapy or surgery is often selected. Because of anatomical accessibility to the liver cyst and the patient’s wish, we performed endoscopic transgastric drainage with insertion of both an internal stent and an external nasocystic tube. Sclerotherapy with minocycline hydrochloride was performed through the nasocystic tube, and the liver cyst shrunk completely without any complications. This is the first reported method of administering minocycline hydrochloride through a nasocystic tube, which can be a therapeutic option for patients with symptomatic liver cysts.
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publisher Wiley
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-bb4309b8d125404a9738425b1d1eb77f2025-08-20T02:18:50ZengWileyCase Reports in Gastrointestinal Medicine2090-65362024-01-01202410.1155/2024/6942345Symptomatic Liver Cyst Successfully Treated with Transgastric Drainage and Sclerotherapy Using Minocycline HydrochlorideKengo Yoshitomi0Yudai Koya1Koichiro Miyagawa2Yuki Maruno3Koki Yamaguchi4Ryuta Taniguchi5Koji Onitsuka6Yoshitaka Sakamoto7Shinji Oe8Masaru Harada9Department of GastroenterologyDepartment of GastroenterologyThe Third Department of Internal MedicineDepartment of GastroenterologyDepartment of GastroenterologyDepartment of SurgeryDepartment of SurgeryDepartment of SurgeryThe Third Department of Internal MedicineThe Third Department of Internal MedicineA liver cyst is hepatic fluid-filled cavities often detected in clinical surveillances such as a health examination. Although the liver cyst is usually asymptomatic and observed without any therapeutic intervention, it can be symptomatic and needs treatment due to its enlargement, hemorrhage, and infection. A 74-year-old woman presented with upper abdominal pain and a huge liver cyst in the left lobe. Several examinations including image findings revealed that the symptom could be derived from the liver cyst. Although there is no definite guideline of treatment for symptomatic liver cysts, percutaneous ultrasound-guided drainage with sclerotherapy or surgery is often selected. Because of anatomical accessibility to the liver cyst and the patient’s wish, we performed endoscopic transgastric drainage with insertion of both an internal stent and an external nasocystic tube. Sclerotherapy with minocycline hydrochloride was performed through the nasocystic tube, and the liver cyst shrunk completely without any complications. This is the first reported method of administering minocycline hydrochloride through a nasocystic tube, which can be a therapeutic option for patients with symptomatic liver cysts.http://dx.doi.org/10.1155/2024/6942345
spellingShingle Kengo Yoshitomi
Yudai Koya
Koichiro Miyagawa
Yuki Maruno
Koki Yamaguchi
Ryuta Taniguchi
Koji Onitsuka
Yoshitaka Sakamoto
Shinji Oe
Masaru Harada
Symptomatic Liver Cyst Successfully Treated with Transgastric Drainage and Sclerotherapy Using Minocycline Hydrochloride
Case Reports in Gastrointestinal Medicine
title Symptomatic Liver Cyst Successfully Treated with Transgastric Drainage and Sclerotherapy Using Minocycline Hydrochloride
title_full Symptomatic Liver Cyst Successfully Treated with Transgastric Drainage and Sclerotherapy Using Minocycline Hydrochloride
title_fullStr Symptomatic Liver Cyst Successfully Treated with Transgastric Drainage and Sclerotherapy Using Minocycline Hydrochloride
title_full_unstemmed Symptomatic Liver Cyst Successfully Treated with Transgastric Drainage and Sclerotherapy Using Minocycline Hydrochloride
title_short Symptomatic Liver Cyst Successfully Treated with Transgastric Drainage and Sclerotherapy Using Minocycline Hydrochloride
title_sort symptomatic liver cyst successfully treated with transgastric drainage and sclerotherapy using minocycline hydrochloride
url http://dx.doi.org/10.1155/2024/6942345
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