M6A-Methylated circRAPGEF5 drives lung adenocarcinoma progression and metastasis via IGF2BP2/NUP160-mediated autophagy suppression

M6A-Methylated circRAPGEF5 drives lung adenocarcinoma progression and metastasis via IGF2BP2/NUP160-mediated autophagy suppression

Abstract Background Lung adenocarcinoma (LUAD), the predominant histological subtype of non-small cell lung cancer, demonstrates critical regulatory involvement of RNA-binding proteins (RBPs) and circular RNAs (circRNAs) in tumorigenic processes. Emerging evidence highlights the circRNA-autophagy re...

Full description

Saved in:
Bibliographic Details
Main Authors: Liqun Ling, Tianqi Hu, Chenkang Zhou, Yingjie Dai, Lijuan Hu, Yuxin Chen, Zhaoting Hu, Kate Huang, Jie Chen, Yumin Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Cancer
Online Access:https://doi.org/10.1186/s12943-025-02399-3
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items