Capture and detection of extracellular vesicles derived from human breast cancer cells using a 3D self-assembled nanostructured SiO2 microfluidic chip

Capture and detection of extracellular vesicles derived from human breast cancer cells using a 3D self-assembled nanostructured SiO2 microfluidic chip

Abstract Background Tumor-derived extracellular vesicles offer a minimally invasive approach to evaluate tumor progression and metastasis. However, detecting biomarkers, such as extracellular vesicles in body fluids during the early stages of disease, remains a significant challenge. Conventional me...

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Bibliographic Details
Main Authors: Carolina Cabeza, Felipe Rojas, Lorena Lobos-González, Dominique Lemaitre, Juan Villena, María Luisa Cordero, Natalia Hassan, Rina Ortiz
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Biological Engineering
Subjects:
Extracellular vesicles
Biosensors
Microfluidic chip
Liquid biopsy
Breast cancer
Online Access:https://doi.org/10.1186/s13036-025-00512-0
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