Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces
Orthodontic force-induced stresses cause dynamic alterations within the extracellular matrix and within the cytoskeleton of cells in the periodontal ligament and alveolar bone, mediating bone remodelling, ultimately enabling orthodontic tooth movement. In the periodontal ligament and alveolar bone,...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2015/876509 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832558200648368128 |
|---|---|
| author | L. Feller R. A. G. Khammissa I. Schechter G. Thomadakis J. Fourie J. Lemmer |
| author_facet | L. Feller R. A. G. Khammissa I. Schechter G. Thomadakis J. Fourie J. Lemmer |
| author_sort | L. Feller |
| collection | DOAJ |
| description | Orthodontic force-induced stresses cause dynamic alterations within the extracellular matrix and within the cytoskeleton of cells in the periodontal ligament and alveolar bone, mediating bone remodelling, ultimately enabling orthodontic tooth movement. In the periodontal ligament and alveolar bone, the mechanically induced tensile strains upregulate the expression of osteogenic genes resulting in bone formation, while mechanically induced compressive strains mediate predominantly catabolic tissue changes and bone resorption. In this review article we summarize some of the currently known biological events occurring in the periodontal ligament and in the alveolar bone in response to application of orthodontic forces and how these facilitate tooth movement. |
| format | Article |
| id | doaj-art-bb3d1a0122664ffd8bf1ea6cae802f0c |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-bb3d1a0122664ffd8bf1ea6cae802f0c2025-02-03T01:33:06ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/876509876509Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic ForcesL. Feller0R. A. G. Khammissa1I. Schechter2G. Thomadakis3J. Fourie4J. Lemmer5Department of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South AfricaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South AfricaSchulich Faculty of Chemistry, Technion-Israel Institute of Technology, 32000 Haifa, IsraelPrivate Practice, 15 School Road, Morningside, Johannesburg 2057, South AfricaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South AfricaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South AfricaOrthodontic force-induced stresses cause dynamic alterations within the extracellular matrix and within the cytoskeleton of cells in the periodontal ligament and alveolar bone, mediating bone remodelling, ultimately enabling orthodontic tooth movement. In the periodontal ligament and alveolar bone, the mechanically induced tensile strains upregulate the expression of osteogenic genes resulting in bone formation, while mechanically induced compressive strains mediate predominantly catabolic tissue changes and bone resorption. In this review article we summarize some of the currently known biological events occurring in the periodontal ligament and in the alveolar bone in response to application of orthodontic forces and how these facilitate tooth movement.http://dx.doi.org/10.1155/2015/876509 |
| spellingShingle | L. Feller R. A. G. Khammissa I. Schechter G. Thomadakis J. Fourie J. Lemmer Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces The Scientific World Journal |
| title | Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces |
| title_full | Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces |
| title_fullStr | Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces |
| title_full_unstemmed | Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces |
| title_short | Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces |
| title_sort | biological events in periodontal ligament and alveolar bone associated with application of orthodontic forces |
| url | http://dx.doi.org/10.1155/2015/876509 |
| work_keys_str_mv | AT lfeller biologicaleventsinperiodontalligamentandalveolarboneassociatedwithapplicationoforthodonticforces AT ragkhammissa biologicaleventsinperiodontalligamentandalveolarboneassociatedwithapplicationoforthodonticforces AT ischechter biologicaleventsinperiodontalligamentandalveolarboneassociatedwithapplicationoforthodonticforces AT gthomadakis biologicaleventsinperiodontalligamentandalveolarboneassociatedwithapplicationoforthodonticforces AT jfourie biologicaleventsinperiodontalligamentandalveolarboneassociatedwithapplicationoforthodonticforces AT jlemmer biologicaleventsinperiodontalligamentandalveolarboneassociatedwithapplicationoforthodonticforces |