Report of chronic myeloid leukemia SMS Medical College Hospital, Jaipur
This is a retrospective analysis of patients of chronic myeloid leukemia (CML) registered and under treatment at the Leukemia Lymphoma Clinic at the Birla Cancer Center, SMS Medical College Hospital, Jaipur. Approximately, two-thirds of the patients are getting imatinib mesylate (IM) through the Gli...
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| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2013-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2013;volume=34;issue=3;spage=177;epage=179;aulast=Malhotra |
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| author | Hemant Malhotra Rajesh Sharma Yogender Singh Hemant Chaturvedi |
| author_facet | Hemant Malhotra Rajesh Sharma Yogender Singh Hemant Chaturvedi |
| author_sort | Hemant Malhotra |
| collection | DOAJ |
| description | This is a retrospective analysis of patients of chronic myeloid leukemia (CML) registered and under treatment at the Leukemia Lymphoma Clinic at the Birla Cancer Center, SMS Medical College Hospital, Jaipur. Approximately, two-thirds of the patients are getting imatinib mesylate (IM) through the Glivec International Patient Assistance Program while the rest are on generic IM. In addition to comparison of hematological and molecular responses in the Glivec versus the genetic group, in this analysis, an attempt is also made to assess the socio-economic (SE) status of the patients and its effect on the response rates. Of the 213 patients studied, most (28.6%) are in the age group between 30 years and 40 years and the mean age of the patients in 39 years, a good decade younger that in the west. There is a suggestion that patients in lower SE class present with higher Sokal scores and with more disease burden. Possibly hematological responses are similar with both Glivec and generic IM. No comment can be made with regards to molecular response between the two groups as a significant number of patients in the Glivec arm (42%) do not have molecular assessment because of economic reasons. CML is a common and challenging disease in the developing world with patients presenting at an earlier age with more advanced disease. SE factors play a significant role in therapy and disease monitoring decision making and may impact on response rates and prognosis. |
| format | Article |
| id | doaj-art-bb36f9a552c54e44a516e9d0a7988027 |
| institution | DOAJ |
| issn | 0971-5851 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-bb36f9a552c54e44a516e9d0a79880272025-08-20T03:03:50ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512013-01-0134317717910.4103/0971-5851.123723Report of chronic myeloid leukemia SMS Medical College Hospital, JaipurHemant MalhotraRajesh SharmaYogender SinghHemant ChaturvediThis is a retrospective analysis of patients of chronic myeloid leukemia (CML) registered and under treatment at the Leukemia Lymphoma Clinic at the Birla Cancer Center, SMS Medical College Hospital, Jaipur. Approximately, two-thirds of the patients are getting imatinib mesylate (IM) through the Glivec International Patient Assistance Program while the rest are on generic IM. In addition to comparison of hematological and molecular responses in the Glivec versus the genetic group, in this analysis, an attempt is also made to assess the socio-economic (SE) status of the patients and its effect on the response rates. Of the 213 patients studied, most (28.6%) are in the age group between 30 years and 40 years and the mean age of the patients in 39 years, a good decade younger that in the west. There is a suggestion that patients in lower SE class present with higher Sokal scores and with more disease burden. Possibly hematological responses are similar with both Glivec and generic IM. No comment can be made with regards to molecular response between the two groups as a significant number of patients in the Glivec arm (42%) do not have molecular assessment because of economic reasons. CML is a common and challenging disease in the developing world with patients presenting at an earlier age with more advanced disease. SE factors play a significant role in therapy and disease monitoring decision making and may impact on response rates and prognosis.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2013;volume=34;issue=3;spage=177;epage=179;aulast=MalhotraChronic myeloid leukemiachronic phaseJaipur |
| spellingShingle | Hemant Malhotra Rajesh Sharma Yogender Singh Hemant Chaturvedi Report of chronic myeloid leukemia SMS Medical College Hospital, Jaipur Indian Journal of Medical and Paediatric Oncology Chronic myeloid leukemia chronic phase Jaipur |
| title | Report of chronic myeloid leukemia SMS Medical College Hospital, Jaipur |
| title_full | Report of chronic myeloid leukemia SMS Medical College Hospital, Jaipur |
| title_fullStr | Report of chronic myeloid leukemia SMS Medical College Hospital, Jaipur |
| title_full_unstemmed | Report of chronic myeloid leukemia SMS Medical College Hospital, Jaipur |
| title_short | Report of chronic myeloid leukemia SMS Medical College Hospital, Jaipur |
| title_sort | report of chronic myeloid leukemia sms medical college hospital jaipur |
| topic | Chronic myeloid leukemia chronic phase Jaipur |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2013;volume=34;issue=3;spage=177;epage=179;aulast=Malhotra |
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