Oral olsalazine/ellagic acid/ZnCl2‐modified in situ-forming hydrogels alleviates anxiety/depression-like symptoms and brain neural activity in colitis mice

Oral olsalazine/ellagic acid/ZnCl2‐modified in situ-forming hydrogels alleviates anxiety/depression-like symptoms and brain neural activity in colitis mice

Inflammatory bowel disease (IBD) is a kind of chronic non-specific intestinal inflammatory disease, which accompanied by various abnormal psychological states, such as anxiety and depression. Nevertheless, the pathogenesis of IBD with depression is still unclear. Herein, we synthesized an enable a d...

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Bibliographic Details
Main Authors: Tingting Li, Nianlu Li, Haoyu Sheng, Luyao Zhang, Qian Luo, Sashuang Liu, Yijing Zhao, Wenqiang Chen, Dexiang Liu, Zhen Wang
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Materials Today Bio
Subjects:
Inflammatory bowel disease
Hydrogel
Inflammation
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425006283
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