Skin photobiological effect induced by BL: Clinical manifestation, mechanisms, and protection against photodamages
Over the last decade, the rapid advances of life sciences have significantly increased public awareness and comprehension of dermatological knowledge, resulting in widespread acceptance of scientific skincare in society. The scope of photoprotection has expanded to encompass not only ultraviolet rad...
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KeAi Communications Co., Ltd.
2024-09-01
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| Series: | Journal of Dermatologic Science and Cosmetic Technology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950306X24000402 |
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| author | Tao Zhang Malyn Ungsurungsie Liu Yue Junxiang Li Baoxia Zhuang Wenyu Ding Xuhui Li |
| author_facet | Tao Zhang Malyn Ungsurungsie Liu Yue Junxiang Li Baoxia Zhuang Wenyu Ding Xuhui Li |
| author_sort | Tao Zhang |
| collection | DOAJ |
| description | Over the last decade, the rapid advances of life sciences have significantly increased public awareness and comprehension of dermatological knowledge, resulting in widespread acceptance of scientific skincare in society. The scope of photoprotection has expanded to encompass not only ultraviolet radiation but also visible light (including blue light). Furthermore, photoprotection methods have evolved from light blocking to the repair of cellular damage caused by prolonged light exposure via biological signaling pathways. Blue light (BL) is the portion of sunlight between 400 nm（violet）and 500 nm (cyan), that can penetrate deep into biological tissues, with up to 20 % reaching subcutaneous tissues. Similar to UV damage, BL can cause oxidative stress, persistent pigmentation, and extracellular matrix degradation, resulting in skin symptoms such as hyperpigmentation, dullness, lack of radiance, uneven skin tone, and wrinkles. This study investigates the clinical manifestations of BL-induced skin photodamages, as well as the underlying biological mechanisms and proposes rational photoaging prevention strategies. |
| format | Article |
| id | doaj-art-bb2160ba61244cddb475d394908dfaa6 |
| institution | Kabale University |
| issn | 2950-306X |
| language | English |
| publishDate | 2024-09-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Journal of Dermatologic Science and Cosmetic Technology |
| spelling | doaj-art-bb2160ba61244cddb475d394908dfaa62025-08-20T03:58:35ZengKeAi Communications Co., Ltd.Journal of Dermatologic Science and Cosmetic Technology2950-306X2024-09-011310004210.1016/j.jdsct.2024.100042Skin photobiological effect induced by BL: Clinical manifestation, mechanisms, and protection against photodamagesTao Zhang0Malyn Ungsurungsie1Liu Yue2Junxiang Li3Baoxia Zhuang4Wenyu Ding5Xuhui Li6Research and Development Center, Better Way (Shanghai) Cosmetics Co. Ltd., Shanghai 201400, China; Corresponding author.Research, Development and Innovation Division, S&J International Enterprises PCL, Bankok 10120, ThailandResearch and Development Center, Better Way (Shanghai) Cosmetics Co. Ltd., Shanghai 201400, ChinaAGECODE R&D CENTER, Yangtze Delta Region Institute of Tsinghua University Zhejiang, Jiaxing 314000, China; Harvest Biotech (Zhejiang) Co., Ltd., Jiaxing 314000, ChinaResearch and Development Center, Better Way (Shanghai) Cosmetics Co. Ltd., Shanghai 201400, ChinaAGECODE R&D CENTER, Yangtze Delta Region Institute of Tsinghua University Zhejiang, Jiaxing 314000, China; Harvest Biotech (Zhejiang) Co., Ltd., Jiaxing 314000, ChinaAGECODE R&D CENTER, Yangtze Delta Region Institute of Tsinghua University Zhejiang, Jiaxing 314000, China; Zhejiang Provincial Key Laboratory of Applied Enzymology, Yangtze Delta Region Institute of Tsinghua University, Jiaxing 314000, ChinaOver the last decade, the rapid advances of life sciences have significantly increased public awareness and comprehension of dermatological knowledge, resulting in widespread acceptance of scientific skincare in society. The scope of photoprotection has expanded to encompass not only ultraviolet radiation but also visible light (including blue light). Furthermore, photoprotection methods have evolved from light blocking to the repair of cellular damage caused by prolonged light exposure via biological signaling pathways. Blue light (BL) is the portion of sunlight between 400 nm（violet）and 500 nm (cyan), that can penetrate deep into biological tissues, with up to 20 % reaching subcutaneous tissues. Similar to UV damage, BL can cause oxidative stress, persistent pigmentation, and extracellular matrix degradation, resulting in skin symptoms such as hyperpigmentation, dullness, lack of radiance, uneven skin tone, and wrinkles. This study investigates the clinical manifestations of BL-induced skin photodamages, as well as the underlying biological mechanisms and proposes rational photoaging prevention strategies.http://www.sciencedirect.com/science/article/pii/S2950306X24000402Blue lightSkin pigmentationPhotoaging |
| spellingShingle | Tao Zhang Malyn Ungsurungsie Liu Yue Junxiang Li Baoxia Zhuang Wenyu Ding Xuhui Li Skin photobiological effect induced by BL: Clinical manifestation, mechanisms, and protection against photodamages Journal of Dermatologic Science and Cosmetic Technology Blue light Skin pigmentation Photoaging |
| title | Skin photobiological effect induced by BL: Clinical manifestation, mechanisms, and protection against photodamages |
| title_full | Skin photobiological effect induced by BL: Clinical manifestation, mechanisms, and protection against photodamages |
| title_fullStr | Skin photobiological effect induced by BL: Clinical manifestation, mechanisms, and protection against photodamages |
| title_full_unstemmed | Skin photobiological effect induced by BL: Clinical manifestation, mechanisms, and protection against photodamages |
| title_short | Skin photobiological effect induced by BL: Clinical manifestation, mechanisms, and protection against photodamages |
| title_sort | skin photobiological effect induced by bl clinical manifestation mechanisms and protection against photodamages |
| topic | Blue light Skin pigmentation Photoaging |
| url | http://www.sciencedirect.com/science/article/pii/S2950306X24000402 |
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