Staphylococcus lugdunensis Endocarditis Complicated by Embolism in an 18-Year-Old Woman with Mitral Valve Prolapse

Staphylococcus lugdunensis is a coagulase-negative staphylococcus (CNS). It is a major cause of prosthetic valve endocarditis; mitral valve prolapse (MVP) has emerged as a prominent predisposing structural cardiac abnormality. We describe a case of Staphylococcus lugdunensis endocarditis in an 18-y...

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Main Authors: Rosaria Pecoraro, Antonino Tuttolomondo, Gaspare Parrinello, Antonio Pinto, Giuseppe Licata
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2013/730924
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author Rosaria Pecoraro
Antonino Tuttolomondo
Gaspare Parrinello
Antonio Pinto
Giuseppe Licata
author_facet Rosaria Pecoraro
Antonino Tuttolomondo
Gaspare Parrinello
Antonio Pinto
Giuseppe Licata
author_sort Rosaria Pecoraro
collection DOAJ
description Staphylococcus lugdunensis is a coagulase-negative staphylococcus (CNS). It is a major cause of prosthetic valve endocarditis; mitral valve prolapse (MVP) has emerged as a prominent predisposing structural cardiac abnormality. We describe a case of Staphylococcus lugdunensis endocarditis in an 18-year-old woman with preexisting mitral valve prolapse complaining of fever, a one-month history of continuous-remittent fever ( 38.6°C). The transthoracic echocardiogram revealed large vegetation on the anterior mitral valve leaflet flopping from the atrial side to the ventricular side. Five sets of blood cultures were positive for coagulase-negative staphylococci. During hospitalization, after two weeks of antibiotic therapy, the patient complained of sudden pain in her right leg associated with numbness. Lower limb arterial Doppler ultrasound showed an arterial thrombosis of right common iliac artery. Transfemoral iliac embolectomy was promptly performed and on septic embolus S. lugdunensis with the same antibiotic sensitivity and the same MIC values was again isolated. Our patient underwent cardiac surgery: triangular resection of the A2 with removal of infected tissue including vegetation. Our case is an example of infective endocarditis by S. lugdunensis on native mitral valve in a young woman of 18 with anamnesis valve prolapse.
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spelling doaj-art-bb1f75aee66440d5ab421e3d862317a92025-08-20T02:19:11ZengWileyCase Reports in Infectious Diseases2090-66252090-66332013-01-01201310.1155/2013/730924730924Staphylococcus lugdunensis Endocarditis Complicated by Embolism in an 18-Year-Old Woman with Mitral Valve ProlapseRosaria Pecoraro0Antonino Tuttolomondo1Gaspare Parrinello2Antonio Pinto3Giuseppe Licata4Dipartimento Biomedico di Medicina Interna e Specialistica, Università degli Studi di Palermo, 90127 Palermo, ItalyDipartimento Biomedico di Medicina Interna e Specialistica, Università degli Studi di Palermo, 90127 Palermo, ItalyDipartimento Biomedico di Medicina Interna e Specialistica, Università degli Studi di Palermo, 90127 Palermo, ItalyDipartimento Biomedico di Medicina Interna e Specialistica, Università degli Studi di Palermo, 90127 Palermo, ItalyDipartimento Biomedico di Medicina Interna e Specialistica, Università degli Studi di Palermo, 90127 Palermo, ItalyStaphylococcus lugdunensis is a coagulase-negative staphylococcus (CNS). It is a major cause of prosthetic valve endocarditis; mitral valve prolapse (MVP) has emerged as a prominent predisposing structural cardiac abnormality. We describe a case of Staphylococcus lugdunensis endocarditis in an 18-year-old woman with preexisting mitral valve prolapse complaining of fever, a one-month history of continuous-remittent fever ( 38.6°C). The transthoracic echocardiogram revealed large vegetation on the anterior mitral valve leaflet flopping from the atrial side to the ventricular side. Five sets of blood cultures were positive for coagulase-negative staphylococci. During hospitalization, after two weeks of antibiotic therapy, the patient complained of sudden pain in her right leg associated with numbness. Lower limb arterial Doppler ultrasound showed an arterial thrombosis of right common iliac artery. Transfemoral iliac embolectomy was promptly performed and on septic embolus S. lugdunensis with the same antibiotic sensitivity and the same MIC values was again isolated. Our patient underwent cardiac surgery: triangular resection of the A2 with removal of infected tissue including vegetation. Our case is an example of infective endocarditis by S. lugdunensis on native mitral valve in a young woman of 18 with anamnesis valve prolapse.http://dx.doi.org/10.1155/2013/730924
spellingShingle Rosaria Pecoraro
Antonino Tuttolomondo
Gaspare Parrinello
Antonio Pinto
Giuseppe Licata
Staphylococcus lugdunensis Endocarditis Complicated by Embolism in an 18-Year-Old Woman with Mitral Valve Prolapse
Case Reports in Infectious Diseases
title Staphylococcus lugdunensis Endocarditis Complicated by Embolism in an 18-Year-Old Woman with Mitral Valve Prolapse
title_full Staphylococcus lugdunensis Endocarditis Complicated by Embolism in an 18-Year-Old Woman with Mitral Valve Prolapse
title_fullStr Staphylococcus lugdunensis Endocarditis Complicated by Embolism in an 18-Year-Old Woman with Mitral Valve Prolapse
title_full_unstemmed Staphylococcus lugdunensis Endocarditis Complicated by Embolism in an 18-Year-Old Woman with Mitral Valve Prolapse
title_short Staphylococcus lugdunensis Endocarditis Complicated by Embolism in an 18-Year-Old Woman with Mitral Valve Prolapse
title_sort staphylococcus lugdunensis endocarditis complicated by embolism in an 18 year old woman with mitral valve prolapse
url http://dx.doi.org/10.1155/2013/730924
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