Overcoming challenges of developing a live-attenuated dengue vaccine and the path forward

Introduction: The WHO declared dengue a grade 3 emergency, underscoring an urgent need for safe and effective vaccines. Challenges have hindered progress with such vaccines, including selection of an appropriate backbone, proper viral attenuation with balanced immunogenicity/reactogenicity, evaluati...

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Bibliographic Details
Main Authors: Dr Walid Kandeil, Dr Mayuri Sharma
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224007574
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