Nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae in healthy children
Streptococcus pneumoniae carriage is a risk factor for the development of respiratory system infections and the spread of penicillin-resistant strains. The aim of this study was to investigate nasopharyngeal carriage of S. pneumoniae in healthy children and resistance to penicillin and other...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2007-10-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/2569 |
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| _version_ | 1850024076805931008 |
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| author | Arzu Uzuner Arzu Ilki Mehmet Akman Ercan Gündoğdu Riza Erbölükbaş Omer Kokaçya Türkan Mengüç Sibel Kalaça Güner Söyletir |
| author_facet | Arzu Uzuner Arzu Ilki Mehmet Akman Ercan Gündoğdu Riza Erbölükbaş Omer Kokaçya Türkan Mengüç Sibel Kalaça Güner Söyletir |
| author_sort | Arzu Uzuner |
| collection | DOAJ |
| description |
Streptococcus pneumoniae carriage is a risk factor for the development of respiratory system infections and the spread of penicillin-resistant strains. The aim of this study was to investigate nasopharyngeal carriage of S. pneumoniae in healthy children and resistance to penicillin and other antimicrobials and to assess related risk factors. Nasopharyngeal specimens collected from healthy children less than six years of age, visiting a Mother and Child Health Center for health control, were investigated microbiologically between February-March 2004. Carriage rate was 37.2% (n=112/301); 33.9% intermediate and 5.4% high penicillin resistance were detected. According to multivariate analysis, carriage rate was inversely related to number of rooms (OR:0.574) and child age (OR:0.978), while penicillin resistance was correlated well with antibiotic use in the last two months (OR:2.193). Decreased sensitivity plus resistance to other antimicrobials were: trimethoprim-sulfamethoxazole (TMP-SMX) 45.6%; erythromycin 16.1%, tetracycline 16.1%; clindamycin 9.8%, and ofloxacin 3.6% in pneumococcal isolates, which increased significantly (p |
| format | Article |
| id | doaj-art-bb0bce07d86148c19879e42564688d03 |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2007-10-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-bb0bce07d86148c19879e42564688d032025-08-20T03:01:12ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212007-10-01494Nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae in healthy childrenArzu Uzuner0Arzu IlkiMehmet AkmanErcan GündoğduRiza ErbölükbaşOmer KokaçyaTürkan MengüçSibel KalaçaGüner SöyletirDepartment of Family Medicine, Marmara University, Istanbul, Turkey. Streptococcus pneumoniae carriage is a risk factor for the development of respiratory system infections and the spread of penicillin-resistant strains. The aim of this study was to investigate nasopharyngeal carriage of S. pneumoniae in healthy children and resistance to penicillin and other antimicrobials and to assess related risk factors. Nasopharyngeal specimens collected from healthy children less than six years of age, visiting a Mother and Child Health Center for health control, were investigated microbiologically between February-March 2004. Carriage rate was 37.2% (n=112/301); 33.9% intermediate and 5.4% high penicillin resistance were detected. According to multivariate analysis, carriage rate was inversely related to number of rooms (OR:0.574) and child age (OR:0.978), while penicillin resistance was correlated well with antibiotic use in the last two months (OR:2.193). Decreased sensitivity plus resistance to other antimicrobials were: trimethoprim-sulfamethoxazole (TMP-SMX) 45.6%; erythromycin 16.1%, tetracycline 16.1%; clindamycin 9.8%, and ofloxacin 3.6% in pneumococcal isolates, which increased significantly (phttps://turkjpediatr.org/article/view/2569 |
| spellingShingle | Arzu Uzuner Arzu Ilki Mehmet Akman Ercan Gündoğdu Riza Erbölükbaş Omer Kokaçya Türkan Mengüç Sibel Kalaça Güner Söyletir Nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae in healthy children The Turkish Journal of Pediatrics |
| title | Nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae in healthy children |
| title_full | Nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae in healthy children |
| title_fullStr | Nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae in healthy children |
| title_full_unstemmed | Nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae in healthy children |
| title_short | Nasopharyngeal carriage of penicillin-resistant Streptococcus pneumoniae in healthy children |
| title_sort | nasopharyngeal carriage of penicillin resistant streptococcus pneumoniae in healthy children |
| url | https://turkjpediatr.org/article/view/2569 |
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