Short‐Term Cardiovascular Sequelae Following In‐Office Posterior Nasal Nerve Cryoablation

ABSTRACT Objective Evaluate the post‐procedural cardiovascular effects of posterior nasal nerve (PNN) cryoablation in comparison to inferior turbinate reduction (ITR). Methods Patients over 18 years of age who underwent in‐office PNN cryoablation or ITR via submucosal resection via radiofrequency ab...

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Main Authors: Jackson King, Lane D. Squires, Daniel Cates, Machelle Wilson, E. B. Strong, Toby Steele
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Laryngoscope Investigative Otolaryngology
Subjects:
Online Access:https://doi.org/10.1002/lio2.70132
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author Jackson King
Lane D. Squires
Daniel Cates
Machelle Wilson
E. B. Strong
Toby Steele
author_facet Jackson King
Lane D. Squires
Daniel Cates
Machelle Wilson
E. B. Strong
Toby Steele
author_sort Jackson King
collection DOAJ
description ABSTRACT Objective Evaluate the post‐procedural cardiovascular effects of posterior nasal nerve (PNN) cryoablation in comparison to inferior turbinate reduction (ITR). Methods Patients over 18 years of age who underwent in‐office PNN cryoablation or ITR via submucosal resection via radiofrequency ablation between 2019 and 2022 were enrolled. Cardiovascular parameters including systolic blood pressure (SBP), heart rate (HR), in addition to visual analog pain scale (VAS), were collected at baseline and perioperatively. Maximum changes and time to return to baseline were recorded. Results A total of 25 patients were enrolled in the study (16 PNN, 9 ITR). The median maximum change in SBP in the PNN and ITR groups was significant at 36.5 mmHg (IQR 22,50) and 11 mmHg (IQR 0,17) respectively (p = 0.007). The median time to return to baseline for SBP was significantly greater at 57.5 min (IQR 30,75) in the PNN group compared to 8.5 (IQR 0,34) in the ITR group (p = 0.026). The median duration of time post procedure to the maximal SBP recording for the PNN group was 32.5 min in comparison to 5 min in the ITR group (p = 0.083). No differences in HR were noted (p = 0.293). Conclusion PNN cryoablation is associated with greater and prolonged effects on SBP in comparison to ITR when using a similar in‐office anesthesia protocol. Surgeons offering this procedure should be aware of these effects when counseling patients and developing a protocol for post‐procedure monitoring. Level of Evidence 2
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spelling doaj-art-bb0b4884bd0645f28e2e6883fca9269e2025-08-20T02:22:03ZengWileyLaryngoscope Investigative Otolaryngology2378-80382025-06-01103n/an/a10.1002/lio2.70132Short‐Term Cardiovascular Sequelae Following In‐Office Posterior Nasal Nerve CryoablationJackson King0Lane D. Squires1Daniel Cates2Machelle Wilson3E. B. Strong4Toby Steele5Department of Otolaryngology, Head and Neck Surgery University of California Davis California USADepartment of Otolaryngology, Head and Neck Surgery University of California Davis California USADepartment of Otolaryngology, Head and Neck Surgery University of California San Diego California USADepartment of Public Health Sciences, Division of Biostatistics University of California Davis California USADepartment of Otolaryngology, Head and Neck Surgery University of California Davis California USADepartment of Otolaryngology, Head and Neck Surgery University of California Davis California USAABSTRACT Objective Evaluate the post‐procedural cardiovascular effects of posterior nasal nerve (PNN) cryoablation in comparison to inferior turbinate reduction (ITR). Methods Patients over 18 years of age who underwent in‐office PNN cryoablation or ITR via submucosal resection via radiofrequency ablation between 2019 and 2022 were enrolled. Cardiovascular parameters including systolic blood pressure (SBP), heart rate (HR), in addition to visual analog pain scale (VAS), were collected at baseline and perioperatively. Maximum changes and time to return to baseline were recorded. Results A total of 25 patients were enrolled in the study (16 PNN, 9 ITR). The median maximum change in SBP in the PNN and ITR groups was significant at 36.5 mmHg (IQR 22,50) and 11 mmHg (IQR 0,17) respectively (p = 0.007). The median time to return to baseline for SBP was significantly greater at 57.5 min (IQR 30,75) in the PNN group compared to 8.5 (IQR 0,34) in the ITR group (p = 0.026). The median duration of time post procedure to the maximal SBP recording for the PNN group was 32.5 min in comparison to 5 min in the ITR group (p = 0.083). No differences in HR were noted (p = 0.293). Conclusion PNN cryoablation is associated with greater and prolonged effects on SBP in comparison to ITR when using a similar in‐office anesthesia protocol. Surgeons offering this procedure should be aware of these effects when counseling patients and developing a protocol for post‐procedure monitoring. Level of Evidence 2https://doi.org/10.1002/lio2.70132chronic rhinosinusitiscryotherapyendoscopic sinus surgeryendoscopic surgeryrhinitis
spellingShingle Jackson King
Lane D. Squires
Daniel Cates
Machelle Wilson
E. B. Strong
Toby Steele
Short‐Term Cardiovascular Sequelae Following In‐Office Posterior Nasal Nerve Cryoablation
Laryngoscope Investigative Otolaryngology
chronic rhinosinusitis
cryotherapy
endoscopic sinus surgery
endoscopic surgery
rhinitis
title Short‐Term Cardiovascular Sequelae Following In‐Office Posterior Nasal Nerve Cryoablation
title_full Short‐Term Cardiovascular Sequelae Following In‐Office Posterior Nasal Nerve Cryoablation
title_fullStr Short‐Term Cardiovascular Sequelae Following In‐Office Posterior Nasal Nerve Cryoablation
title_full_unstemmed Short‐Term Cardiovascular Sequelae Following In‐Office Posterior Nasal Nerve Cryoablation
title_short Short‐Term Cardiovascular Sequelae Following In‐Office Posterior Nasal Nerve Cryoablation
title_sort short term cardiovascular sequelae following in office posterior nasal nerve cryoablation
topic chronic rhinosinusitis
cryotherapy
endoscopic sinus surgery
endoscopic surgery
rhinitis
url https://doi.org/10.1002/lio2.70132
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