Traditional, complementary, and integrative medicine in the management of ischemic stroke: a narrative review
Ischemic stroke remains a leading cause of mortality and long-term disability worldwide, despite advancements in acute intervention and rehabilitation strategies. Traditional, Complementary, and Integrative Medicine (TCIM) systems; including herbal medicine, acupuncture, and mind-body interventions...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1561688/full |
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| author | S. Sowmiya Rukaiah Fatma Begum L. S. Dhivya Praveen Rajendran N. Harikrishnan Ankul Singh S |
| author_facet | S. Sowmiya Rukaiah Fatma Begum L. S. Dhivya Praveen Rajendran N. Harikrishnan Ankul Singh S |
| author_sort | S. Sowmiya |
| collection | DOAJ |
| description | Ischemic stroke remains a leading cause of mortality and long-term disability worldwide, despite advancements in acute intervention and rehabilitation strategies. Traditional, Complementary, and Integrative Medicine (TCIM) systems; including herbal medicine, acupuncture, and mind-body interventions are increasingly being explored as adjunct therapies in stroke management. This narrative review evaluates the current evidence supporting TCIM approaches for ischemic stroke, highlighting their potential neuroprotective, anti-inflammatory, antioxidant, and cerebrovascular effects. Particular emphasis is placed on well-studied botanical interventions such as Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma], Ginkgo biloba L. [Ginkgoaceae; Ginkgo folium], and Panax ginseng C.A. Mey. [Araliaceae; Ginseng radix]. The review discusses the mechanisms of action, clinical trial outcomes, and integration challenges, while underscoring the need for standardization, quality control, and rigorous scientific validation. This work aims to support informed decisions regarding the integration of evidence-based TCIM practices into conventional stroke care protocols. |
| format | Article |
| id | doaj-art-bb074637dfea49f0aac24ff38b9f798d |
| institution | DOAJ |
| issn | 1663-9812 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj-art-bb074637dfea49f0aac24ff38b9f798d2025-08-20T03:21:46ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-05-011610.3389/fphar.2025.15616881561688Traditional, complementary, and integrative medicine in the management of ischemic stroke: a narrative reviewS. Sowmiya0Rukaiah Fatma Begum1L. S. Dhivya2Praveen Rajendran3N. Harikrishnan4Ankul Singh S5Department of Pharmacology, Dr M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, IndiaInstitute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, IndiaDepartment of Pharmaceutical Chemistry, Dr M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, IndiaDepartment of Pharmacology, Dr M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, IndiaDepartment of pharmaceutical analysis, Dr M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, IndiaDepartment of Pharmacology, Dr M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, IndiaIschemic stroke remains a leading cause of mortality and long-term disability worldwide, despite advancements in acute intervention and rehabilitation strategies. Traditional, Complementary, and Integrative Medicine (TCIM) systems; including herbal medicine, acupuncture, and mind-body interventions are increasingly being explored as adjunct therapies in stroke management. This narrative review evaluates the current evidence supporting TCIM approaches for ischemic stroke, highlighting their potential neuroprotective, anti-inflammatory, antioxidant, and cerebrovascular effects. Particular emphasis is placed on well-studied botanical interventions such as Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma], Ginkgo biloba L. [Ginkgoaceae; Ginkgo folium], and Panax ginseng C.A. Mey. [Araliaceae; Ginseng radix]. The review discusses the mechanisms of action, clinical trial outcomes, and integration challenges, while underscoring the need for standardization, quality control, and rigorous scientific validation. This work aims to support informed decisions regarding the integration of evidence-based TCIM practices into conventional stroke care protocols.https://www.frontiersin.org/articles/10.3389/fphar.2025.1561688/fullischemic stroketraditionalcomplementaryand integrative medicineneuroinflammationoxidative stress |
| spellingShingle | S. Sowmiya Rukaiah Fatma Begum L. S. Dhivya Praveen Rajendran N. Harikrishnan Ankul Singh S Traditional, complementary, and integrative medicine in the management of ischemic stroke: a narrative review Frontiers in Pharmacology ischemic stroke traditional complementary and integrative medicine neuroinflammation oxidative stress |
| title | Traditional, complementary, and integrative medicine in the management of ischemic stroke: a narrative review |
| title_full | Traditional, complementary, and integrative medicine in the management of ischemic stroke: a narrative review |
| title_fullStr | Traditional, complementary, and integrative medicine in the management of ischemic stroke: a narrative review |
| title_full_unstemmed | Traditional, complementary, and integrative medicine in the management of ischemic stroke: a narrative review |
| title_short | Traditional, complementary, and integrative medicine in the management of ischemic stroke: a narrative review |
| title_sort | traditional complementary and integrative medicine in the management of ischemic stroke a narrative review |
| topic | ischemic stroke traditional complementary and integrative medicine neuroinflammation oxidative stress |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2025.1561688/full |
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