New Nanomicellar Form of Latanoprost 0,005 % in Treatment Open Angle Glaucoma

This article provides a review of Lanpressun®, a new formulations of latanoprost micellar nanoemulsion without benzaltonium chloride (BAK). The pharmacokinetics and pharmacodynamics of new formulations are presented. Due to innovative delivery system and absence of detergent preseravative (BAK, poli...

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Main Authors: A. S. Dukhanin, A. Sh. Zagidullina, G. A. Azamatova
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2024-06-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/2376
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author A. S. Dukhanin
A. Sh. Zagidullina
G. A. Azamatova
author_facet A. S. Dukhanin
A. Sh. Zagidullina
G. A. Azamatova
author_sort A. S. Dukhanin
collection DOAJ
description This article provides a review of Lanpressun®, a new formulations of latanoprost micellar nanoemulsion without benzaltonium chloride (BAK). The pharmacokinetics and pharmacodynamics of new formulations are presented. Due to innovative delivery system and absence of detergent preseravative (BAK, poliquaternium and others) Lanpressun® possess better tolerability and safety to ocular surface, that provides patients adherence to longer therapy. The article presents the results of clinical trials demonstrating high hypotensive efficacy of Lanpressun®. Literature analysis of studies on safety and effect on ocular surface shows good tolerability of preservative­free latanoprost nanoemulsion. The authors give the assessment of Lanpressun® future perspectives in treatment of patients with open­angle glaucoma
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publishDate 2024-06-01
publisher Ophthalmology Publishing Group
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series Oftalʹmologiâ
spelling doaj-art-bb022d2aba7f4c778a225b2eb7fc367e2025-08-20T03:22:18ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452024-06-0121237538510.18008/1816-5095-2024-2-375-3851157New Nanomicellar Form of Latanoprost 0,005 % in Treatment Open Angle GlaucomaA. S. Dukhanin0A. Sh. Zagidullina1G. A. Azamatova2N.I. Pirogov Russian National Research Medical UniversityBashkir State Medical UniversityBashkir State Medical University; Branch of Clinic Bud ZdorovThis article provides a review of Lanpressun®, a new formulations of latanoprost micellar nanoemulsion without benzaltonium chloride (BAK). The pharmacokinetics and pharmacodynamics of new formulations are presented. Due to innovative delivery system and absence of detergent preseravative (BAK, poliquaternium and others) Lanpressun® possess better tolerability and safety to ocular surface, that provides patients adherence to longer therapy. The article presents the results of clinical trials demonstrating high hypotensive efficacy of Lanpressun®. Literature analysis of studies on safety and effect on ocular surface shows good tolerability of preservative­free latanoprost nanoemulsion. The authors give the assessment of Lanpressun® future perspectives in treatment of patients with open­angle glaucomahttps://www.ophthalmojournal.com/opht/article/view/2376treatment of glaucomaprostaglandine analogueslatanoprostlanpressun®preservativeocular surface
spellingShingle A. S. Dukhanin
A. Sh. Zagidullina
G. A. Azamatova
New Nanomicellar Form of Latanoprost 0,005 % in Treatment Open Angle Glaucoma
Oftalʹmologiâ
treatment of glaucoma
prostaglandine analogues
latanoprost
lanpressun®
preservative
ocular surface
title New Nanomicellar Form of Latanoprost 0,005 % in Treatment Open Angle Glaucoma
title_full New Nanomicellar Form of Latanoprost 0,005 % in Treatment Open Angle Glaucoma
title_fullStr New Nanomicellar Form of Latanoprost 0,005 % in Treatment Open Angle Glaucoma
title_full_unstemmed New Nanomicellar Form of Latanoprost 0,005 % in Treatment Open Angle Glaucoma
title_short New Nanomicellar Form of Latanoprost 0,005 % in Treatment Open Angle Glaucoma
title_sort new nanomicellar form of latanoprost 0 005 in treatment open angle glaucoma
topic treatment of glaucoma
prostaglandine analogues
latanoprost
lanpressun®
preservative
ocular surface
url https://www.ophthalmojournal.com/opht/article/view/2376
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AT ashzagidullina newnanomicellarformoflatanoprost0005intreatmentopenangleglaucoma
AT gaazamatova newnanomicellarformoflatanoprost0005intreatmentopenangleglaucoma