CAFs-released exosomal CREB1 promotes cell progression and immune evasion in thyroid cancer via the positive regulation of CCL20

CAFs-released exosomal CREB1 promotes cell progression and immune evasion in thyroid cancer via the positive regulation of CCL20

Background Exosomes derived from cancer-associated fibroblasts (CAFs) can affect tumor microenvironment (TME) of thyroid cancer (TC). The cAMP response element binding protein 1 (CREB1) acts as a transcription factor to participate in cancer development. Currently, we aimed to explore the molecular...

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Bibliographic Details
Main Authors: Chen Zheng, Hu Hei, Yifei Zhai, Wenbo Gong, Runfang Zhang, Songtao Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Autoimmunity
Subjects:
CREB1
CCL20
CAFs-derived exosomes
thyroid cancer
immune evasion
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2025.2458324
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