UK cancer vaccine advance – Recognising and realising opportunities
Vaccines have revolutionised the field of medicine, eradicating and controlling many diseases. Recent pandemic vaccine successes have highlighted the accelerated pace of vaccine development and deployment. Leveraging this momentum, attention has shifted to cancer vaccines and personalised cancer vac...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2025-01-01
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| Series: | Cambridge Prisms: Precision Medicine |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S275261432400005X/type/journal_article |
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| author | Charles Craddock Philip Earwaker Matthew Fittall Elisa Fontana Divya Ganesh Marco Gerlinger Qamar Ghafoor Robert P Jones Victoria Kunene Lennard Lee Rebecca Lee Siow-Ming Lee Mark Linch Martin Little Justin Liu Hayley McKenzie Russell Petty David J Pinato Thomas Powles Andrew Protheroe Tim Robinson Paul J Ross Kai Keen Shiu James Spicer Stefan Symeonides Michael Tilby Dale Vimalachandran Jenny Y Wang Andrew Wardley Helen Winter |
| author_facet | Charles Craddock Philip Earwaker Matthew Fittall Elisa Fontana Divya Ganesh Marco Gerlinger Qamar Ghafoor Robert P Jones Victoria Kunene Lennard Lee Rebecca Lee Siow-Ming Lee Mark Linch Martin Little Justin Liu Hayley McKenzie Russell Petty David J Pinato Thomas Powles Andrew Protheroe Tim Robinson Paul J Ross Kai Keen Shiu James Spicer Stefan Symeonides Michael Tilby Dale Vimalachandran Jenny Y Wang Andrew Wardley Helen Winter |
| author_sort | Charles Craddock |
| collection | DOAJ |
| description | Vaccines have revolutionised the field of medicine, eradicating and controlling many diseases. Recent pandemic vaccine successes have highlighted the accelerated pace of vaccine development and deployment. Leveraging this momentum, attention has shifted to cancer vaccines and personalised cancer vaccines, aimed at targeting individual tumour-specific abnormalities. The UK, now regarded for its vaccine capabilities, is an ideal nation for pioneering cancer vaccine trials. This article convened experts to share insights and approaches to navigate the challenges of cancer vaccine development with personalised or precision cancer vaccines, as well as fixed vaccines. Emphasising partnership and proactive strategies, this article outlines the ambition to harness national and local system capabilities in the UK; to work in collaboration with potential pharmaceutic partners; and to seize the opportunity to deliver the pace for rapid advances in cancer vaccine technology. |
| format | Article |
| id | doaj-art-bad7aad4c2d149efaaec954239423b29 |
| institution | Kabale University |
| issn | 2752-6143 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Cambridge Prisms: Precision Medicine |
| spelling | doaj-art-bad7aad4c2d149efaaec954239423b292025-01-20T09:06:33ZengCambridge University PressCambridge Prisms: Precision Medicine2752-61432025-01-01310.1017/pcm.2024.5UK cancer vaccine advance – Recognising and realising opportunitiesCharles Craddock0Philip Earwaker1Matthew Fittall2Elisa Fontana3Divya Ganesh4Marco Gerlinger5Qamar Ghafoor6Robert P Jones7Victoria Kunene8Lennard Lee9https://orcid.org/0000-0002-8993-8438Rebecca Lee10Siow-Ming Lee11Mark Linch12Martin Little13Justin Liu14Hayley McKenzie15Russell Petty16David J Pinato17Thomas Powles18Andrew Protheroe19Tim Robinson20Paul J Ross21Kai Keen Shiu22James Spicer23Stefan Symeonides24Michael Tilby25Dale Vimalachandran26Jenny Y Wang27Andrew Wardley28Helen Winter29University of Warwick Warwick Clinical Trials Unit, Coventry, United Kingdom of Great Britain and Northern IrelandCambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom of Great Britain and Northern IrelandUniversity College London, London, United Kingdom of Great Britain and Northern IrelandSarah Cannon Research UK, London, United Kingdom of Great Britain and Northern IrelandUniversity of Oxford, Oxford, United Kingdom of Great Britain and Northern IrelandBarts Health NHS Trust, London, United Kingdom of Great Britain and Northern IrelandUniversity Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom of Great Britain and Northern IrelandUniversity of Liverpool, Liverpool, United Kingdom of Great Britain and Northern IrelandUniversity Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom of Great Britain and Northern IrelandUniversity of Oxford, Oxford, United Kingdom of Great Britain and Northern IrelandThe Christie NHS Foundation Trust, Manchester, United Kingdom of Great Britain and Northern IrelandUniversity College London Hospitals NHS Foundation Trust, London, United Kingdom of Great Britain and Northern IrelandUniversity College London Hospitals NHS Foundation Trust, London, United Kingdom of Great Britain and Northern IrelandOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom of Great Britain and Northern IrelandLeeds Teaching Hospitals NHS Trust, Leeds, United Kingdom of Great Britain and Northern IrelandUniversity Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom of Great Britain and Northern IrelandUniversity of Dundee, Dundee, United Kingdom of Great Britain and Northern IrelandImperial College London, London, United Kingdom of Great Britain and Northern Ireland Hammersmith Hospitals NHS Trust, London, United Kingdom of Great Britain and Northern Ireland Universita degli Studi del Piemonte Orientale Amedeo Avogadro, Vercelli, ItalyBarts Health NHS Trust, London, United Kingdom of Great Britain and Northern IrelandUniversity of Oxford, Oxford, United Kingdom of Great Britain and Northern IrelandUniversity of Bristol, Bristol, United Kingdom of Great Britain and Northern IrelandGuy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom of Great Britain and Northern IrelandUniversity College London Hospitals NHS Foundation Trust, London, United Kingdom of Great Britain and Northern IrelandKing’s College London, London, United Kingdom of Great Britain and Northern IrelandEdinburgh Cancer Research Centre, Edinburgh, United Kingdom of Great Britain and Northern IrelandUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, United Kingdom of Great Britain and Northern IrelandCountess of Chester Hospital NHS Foundation Trust, Chester, United Kingdom of Great Britain and Northern IrelandUniversity of Oxford, Oxford, United Kingdom of Great Britain and Northern IrelandOutreach Research & Innovation Group Limited, United Kingdom of Great Britain and Northern IrelandUniversity Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom of Great Britain and Northern IrelandVaccines have revolutionised the field of medicine, eradicating and controlling many diseases. Recent pandemic vaccine successes have highlighted the accelerated pace of vaccine development and deployment. Leveraging this momentum, attention has shifted to cancer vaccines and personalised cancer vaccines, aimed at targeting individual tumour-specific abnormalities. The UK, now regarded for its vaccine capabilities, is an ideal nation for pioneering cancer vaccine trials. This article convened experts to share insights and approaches to navigate the challenges of cancer vaccine development with personalised or precision cancer vaccines, as well as fixed vaccines. Emphasising partnership and proactive strategies, this article outlines the ambition to harness national and local system capabilities in the UK; to work in collaboration with potential pharmaceutic partners; and to seize the opportunity to deliver the pace for rapid advances in cancer vaccine technology.https://www.cambridge.org/core/product/identifier/S275261432400005X/type/journal_articleCancerClinical trialsImmunotherapeuticsPersonalized therapiesPrecision oncology |
| spellingShingle | Charles Craddock Philip Earwaker Matthew Fittall Elisa Fontana Divya Ganesh Marco Gerlinger Qamar Ghafoor Robert P Jones Victoria Kunene Lennard Lee Rebecca Lee Siow-Ming Lee Mark Linch Martin Little Justin Liu Hayley McKenzie Russell Petty David J Pinato Thomas Powles Andrew Protheroe Tim Robinson Paul J Ross Kai Keen Shiu James Spicer Stefan Symeonides Michael Tilby Dale Vimalachandran Jenny Y Wang Andrew Wardley Helen Winter UK cancer vaccine advance – Recognising and realising opportunities Cambridge Prisms: Precision Medicine Cancer Clinical trials Immunotherapeutics Personalized therapies Precision oncology |
| title | UK cancer vaccine advance – Recognising and realising opportunities |
| title_full | UK cancer vaccine advance – Recognising and realising opportunities |
| title_fullStr | UK cancer vaccine advance – Recognising and realising opportunities |
| title_full_unstemmed | UK cancer vaccine advance – Recognising and realising opportunities |
| title_short | UK cancer vaccine advance – Recognising and realising opportunities |
| title_sort | uk cancer vaccine advance recognising and realising opportunities |
| topic | Cancer Clinical trials Immunotherapeutics Personalized therapies Precision oncology |
| url | https://www.cambridge.org/core/product/identifier/S275261432400005X/type/journal_article |
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