Salivary Neuropilin-1 as a Promising Biomarker in Smokers with and without Oral Leukoplakia and Oral Cancer Patients: A Clinico-Biochemical Study

Salivary Neuropilin-1 as a Promising Biomarker in Smokers with and without Oral Leukoplakia and Oral Cancer Patients: A Clinico-Biochemical Study

Background: Neuropilin-1 (NRP1) is a transmembrane glycoprotein which has a pivotal role in pathological processes of cancer progression and metastasis. The risk of invasive oral cancer developing from oral leukoplakia is higher, ranging from 3% to 33%. Prior literature has highlighted Neuropilin ov...

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Bibliographic Details
Main Authors: Deepasakthi Jayagopi, Sreedevi Dharman, Selvaraj Jayaraman
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Journal of Indian Academy of Oral Medicine and Radiology
Subjects:
biomarkers
enzyme-linked immunosorbent assay
neuropilin-1
oral leukoplakia
smoking
key message: salivary neuropilin has significant clinical implications such as early detection and screening, monitoring disease progression and prognosis, and targets for therapeutic interventions.
Online Access:https://journals.lww.com/10.4103/jiaomr.jiaomr_10_25
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