Targeting autophagy in HCC treatment: exploiting the CD147 internalization pathway

Targeting autophagy in HCC treatment: exploiting the CD147 internalization pathway

Abstract Background/Aims Chemotherapy resistance in liver cancer is a major clinical issue, with CD147 playing a vital role in this process. However, the specific mechanisms underlying these processes remain largely unknown. This study investigates how CD147 internalization leads to cytoprotective a...

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Bibliographic Details
Main Authors: Meirui Qian, Ziyu Wan, Xue Liang, Lin Jing, Huijie Zhang, Heyao Qin, Wenli Duan, Ruo Chen, Tianjiao Zhang, Qian He, Meng Lu, Jianli Jiang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell Communication and Signaling
Subjects:
CD147
Chemoresistance
Cytoprotective autophagy
G3BP1
SG
Online Access:https://doi.org/10.1186/s12964-024-01956-5
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