Association of depression with severe non-alcoholic fatty liver disease: evidence from the UK Biobank study and Mendelian randomization analysis

Association of depression with severe non-alcoholic fatty liver disease: evidence from the UK Biobank study and Mendelian randomization analysis

Abstract The relationship between depression and severe non-alcoholic fatty liver disease (NAFLD) has not been clearly defined. We conducted a longitudinal cohort study and a two-sample Mendelian randomization (MR) analysis to assess the association of depression with severe NAFLD risk. We used indi...

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Bibliographic Details
Main Authors: Xiaorui Zhou, Juan Liao, Li Liu, Yajing Meng, Dailan Yang, Xuehong Zhang, Lu Long
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Depression
Non-alcoholic fatty liver disease
Prospective studies
Mendelian randomization
Online Access:https://doi.org/10.1038/s41598-024-79100-z
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