Characterizing somatic mutations in ovarian cancer germline risk regions
Abstract Epithelial ovarian cancer (EOC) genetics research has been focused on germline or somatic mutations independently. Emerging evidence suggests that the somatic mutational landscape can be shaped by the germline genetic background. In this study, we aim to unravel the role of somatic alterati...
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| Main Authors: | Ping-Hung Lai, Jonathan P. Tyrer, Paul Pharoah, Simon A. Gayther, Michelle R. Jones, Pei-Chen Peng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08072-1 |
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