DISSEMINATED INTRAVASCULAR COAGULATION IN CHILDREN. DIAGNOSTICS AND TREATMENT
The article focuses on modern approaches to pathophysiology, diagnostics and treatment of disseminated intravascular coagulation. Consumptive coagulopathy is a serious complication and associated with significantly increased mortality in children. The causes of developing disseminated intravascular...
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| Format: | Article |
| Language: | Russian |
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Union of pediatricians of Russia
2010-11-01
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| Series: | Педиатрическая фармакология |
| Online Access: | https://www.pedpharma.ru/jour/article/view/1072 |
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| author | R.F. Tepaev |
| author_facet | R.F. Tepaev |
| author_sort | R.F. Tepaev |
| collection | DOAJ |
| description | The article focuses on modern approaches to pathophysiology, diagnostics and treatment of disseminated intravascular coagulation. Consumptive coagulopathy is a serious complication and associated with significantly increased mortality in children. The causes of developing disseminated intravascular coagulation (DIC) may be a systemic inflammatory response and/or an entry of procoagulant material into bloodstream. Chronic DIC may run with no symptoms whilst the acute DIC may be accompanied with bleeding, thrombosis, and multiorgan failure. The laboratory diagnostics should be serial and determine the combination of blood coagulation indicators. DIC is a secondary clinical manifestation of the core pathology, hence the key objective of an integrated therapy is to treat the core disease. Key words: Disseminated Intravascular Coagulation, causes, pathogenesis, diagnostics, treatment, children. (Pediatric Pharmacology. – 2010; 7(6):27-31) |
| format | Article |
| id | doaj-art-bab0c0ba64de4411b9bb1b28f145c14e |
| institution | DOAJ |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2010-11-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-bab0c0ba64de4411b9bb1b28f145c14e2025-08-20T03:19:42ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892010-11-017627311067DISSEMINATED INTRAVASCULAR COAGULATION IN CHILDREN. DIAGNOSTICS AND TREATMENTR.F. Tepaev0Scientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowThe article focuses on modern approaches to pathophysiology, diagnostics and treatment of disseminated intravascular coagulation. Consumptive coagulopathy is a serious complication and associated with significantly increased mortality in children. The causes of developing disseminated intravascular coagulation (DIC) may be a systemic inflammatory response and/or an entry of procoagulant material into bloodstream. Chronic DIC may run with no symptoms whilst the acute DIC may be accompanied with bleeding, thrombosis, and multiorgan failure. The laboratory diagnostics should be serial and determine the combination of blood coagulation indicators. DIC is a secondary clinical manifestation of the core pathology, hence the key objective of an integrated therapy is to treat the core disease. Key words: Disseminated Intravascular Coagulation, causes, pathogenesis, diagnostics, treatment, children. (Pediatric Pharmacology. – 2010; 7(6):27-31)https://www.pedpharma.ru/jour/article/view/1072 |
| spellingShingle | R.F. Tepaev DISSEMINATED INTRAVASCULAR COAGULATION IN CHILDREN. DIAGNOSTICS AND TREATMENT Педиатрическая фармакология |
| title | DISSEMINATED INTRAVASCULAR COAGULATION IN CHILDREN. DIAGNOSTICS AND TREATMENT |
| title_full | DISSEMINATED INTRAVASCULAR COAGULATION IN CHILDREN. DIAGNOSTICS AND TREATMENT |
| title_fullStr | DISSEMINATED INTRAVASCULAR COAGULATION IN CHILDREN. DIAGNOSTICS AND TREATMENT |
| title_full_unstemmed | DISSEMINATED INTRAVASCULAR COAGULATION IN CHILDREN. DIAGNOSTICS AND TREATMENT |
| title_short | DISSEMINATED INTRAVASCULAR COAGULATION IN CHILDREN. DIAGNOSTICS AND TREATMENT |
| title_sort | disseminated intravascular coagulation in children diagnostics and treatment |
| url | https://www.pedpharma.ru/jour/article/view/1072 |
| work_keys_str_mv | AT rftepaev disseminatedintravascularcoagulationinchildrendiagnosticsandtreatment |