Circadian phase inversion causes insulin resistance in a rat model of night work and jet lag
Abstract Shift workers have an increased risk to develop type 2 diabetes. We aimed to investigate the underlying mechanisms and the role of the timing of food intake by subjecting rats to an acute phase inversion of the light/dark (L/D) cycle. In the first experiment, with food available ad libitum,...
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| Main Authors: | Anhui Wang, Ewout Foppen, Valentina S. Rumanova, Tess Kool, Andries Kalsbeek, Dirk J. Stenvers |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-91485-z |
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