Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature
Kimura’s disease (KD) is a rare chronic inflammatory condition of unknown aetiology. It is a benign disease that might mimic a neoplastic process. It primarily affects the head and neck region, presenting as deep subcutaneous masses, and is often accompanied by triad regional lymphadenopathy, saliva...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2022/5103547 |
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| author | Zahra A. Natsha Islam A. Hamarsheh Rawan S. Utt Bassam Abu Alrob Adnan A. Wahdan |
| author_facet | Zahra A. Natsha Islam A. Hamarsheh Rawan S. Utt Bassam Abu Alrob Adnan A. Wahdan |
| author_sort | Zahra A. Natsha |
| collection | DOAJ |
| description | Kimura’s disease (KD) is a rare chronic inflammatory condition of unknown aetiology. It is a benign disease that might mimic a neoplastic process. It primarily affects the head and neck region, presenting as deep subcutaneous masses, and is often accompanied by triad regional lymphadenopathy, salivary gland involvement, and high serum immunoglobulin E (IgE) levels. Here, we report the second documented case of KD in Palestine diagnosed in a 28-year-old male patient who presented with lymphadenopathy and increased serum immunoglobulin E and G (IgE and IgG) associated with intermittent abdominal pain, generalised fatigue, hepatomegaly, cardiomyopathy, reactive airway disease, peripheral vasculopathy, peripheral neuropathy, and focal segmental glomerulosclerosis. The patient was managed with steroids and an immunosuppressant (Azathioprine) with a moderate response for two years. In 2021, treatment with Mycophenolate Mofetil was initiated, which was more effective than Azathioprine. |
| format | Article |
| id | doaj-art-baae7bea063c45cfbff7f48707abd747 |
| institution | Kabale University |
| issn | 1687-9635 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-baae7bea063c45cfbff7f48707abd7472025-02-03T05:57:27ZengWileyCase Reports in Medicine1687-96352022-01-01202210.1155/2022/5103547Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of LiteratureZahra A. Natsha0Islam A. Hamarsheh1Rawan S. Utt2Bassam Abu Alrob3Adnan A. Wahdan4Al-Quds University Faculty of MedicineAl-Quds University Faculty of MedicineAl-Quds University Faculty of MedicinePalestine Medical ComplexPalestine Medical ComplexKimura’s disease (KD) is a rare chronic inflammatory condition of unknown aetiology. It is a benign disease that might mimic a neoplastic process. It primarily affects the head and neck region, presenting as deep subcutaneous masses, and is often accompanied by triad regional lymphadenopathy, salivary gland involvement, and high serum immunoglobulin E (IgE) levels. Here, we report the second documented case of KD in Palestine diagnosed in a 28-year-old male patient who presented with lymphadenopathy and increased serum immunoglobulin E and G (IgE and IgG) associated with intermittent abdominal pain, generalised fatigue, hepatomegaly, cardiomyopathy, reactive airway disease, peripheral vasculopathy, peripheral neuropathy, and focal segmental glomerulosclerosis. The patient was managed with steroids and an immunosuppressant (Azathioprine) with a moderate response for two years. In 2021, treatment with Mycophenolate Mofetil was initiated, which was more effective than Azathioprine.http://dx.doi.org/10.1155/2022/5103547 |
| spellingShingle | Zahra A. Natsha Islam A. Hamarsheh Rawan S. Utt Bassam Abu Alrob Adnan A. Wahdan Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature Case Reports in Medicine |
| title | Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature |
| title_full | Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature |
| title_fullStr | Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature |
| title_full_unstemmed | Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature |
| title_short | Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature |
| title_sort | atypical presentation of kimura s disease in a male patient a case report and review of literature |
| url | http://dx.doi.org/10.1155/2022/5103547 |
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