Inspiratory Muscle Training and Its Impact on Weaning Success in Mechanically Ventilated ICU Patients: A Systematic Review

Background/Objectives: A major importance is now accorded to respiratory muscle weakness resulting from exposure to invasive mechanical ventilation (IMV) in intensive care unit patients. Some authors suggested that Inspiratory Muscle Training (IMT) could increase the chances of weaning off IMV. This...

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Main Authors: José Luís Alonso-Pérez, Víctor Riquelme-Aguado, Daniel Rodríguez-Prieto, Alejandro López-Mejías, Carlos Romero-Morales, Giacomo Rossettini, Jorge Hugo Villafañe
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Journal of Functional Morphology and Kinesiology
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Online Access:https://www.mdpi.com/2411-5142/10/2/111
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author José Luís Alonso-Pérez
Víctor Riquelme-Aguado
Daniel Rodríguez-Prieto
Alejandro López-Mejías
Carlos Romero-Morales
Giacomo Rossettini
Jorge Hugo Villafañe
author_facet José Luís Alonso-Pérez
Víctor Riquelme-Aguado
Daniel Rodríguez-Prieto
Alejandro López-Mejías
Carlos Romero-Morales
Giacomo Rossettini
Jorge Hugo Villafañe
author_sort José Luís Alonso-Pérez
collection DOAJ
description Background/Objectives: A major importance is now accorded to respiratory muscle weakness resulting from exposure to invasive mechanical ventilation (IMV) in intensive care unit patients. Some authors suggested that Inspiratory Muscle Training (IMT) could increase the chances of weaning off IMV. This systematic review examined the efficacy of IMT on weaning success in mechanically ventilated patients. Methods: A literature search was conducted on PubMed, Cochrane, and PEDro until June 2023. Weaning success, maximum inspiratory pressure (MIP), and Rapid Shallow Breathing Index (RSBI) were the outcome measures included. Results: Seven randomized controlled trials, including 517 participants under IMV for at least 48 h, were included in the review. From a qualitative point of view, a significant increase in MIP and a significant decrease in RSBI were found in the intervention group during the analysis. However, weaning success was the same between the intervention and control groups. No significant association was found between weaning success and the increase of MIP or the decrease of RSBI. Furthermore, it could not be demonstrated that a positive change in MIP or RSBI would increase the weaning success rates. Conclusions: From a qualitative point of view, IMT is effective in increasing MIP and decreasing RSBI. However, IMT has no significant impact on weaning success. Further research is recommended to analyze the effect of IMT on weaning success.
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spelling doaj-art-baadf57cbb0d41f0a7cb550fc551a0852025-08-20T03:24:36ZengMDPI AGJournal of Functional Morphology and Kinesiology2411-51422025-03-0110211110.3390/jfmk10020111Inspiratory Muscle Training and Its Impact on Weaning Success in Mechanically Ventilated ICU Patients: A Systematic ReviewJosé Luís Alonso-Pérez0Víctor Riquelme-Aguado1Daniel Rodríguez-Prieto2Alejandro López-Mejías3Carlos Romero-Morales4Giacomo Rossettini5Jorge Hugo Villafañe6Department of Physiotherapy, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, SpainDepartment of Basic Health Sciences, Rey Juan Carlos University, 28933 Madrid, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, SpainBackground/Objectives: A major importance is now accorded to respiratory muscle weakness resulting from exposure to invasive mechanical ventilation (IMV) in intensive care unit patients. Some authors suggested that Inspiratory Muscle Training (IMT) could increase the chances of weaning off IMV. This systematic review examined the efficacy of IMT on weaning success in mechanically ventilated patients. Methods: A literature search was conducted on PubMed, Cochrane, and PEDro until June 2023. Weaning success, maximum inspiratory pressure (MIP), and Rapid Shallow Breathing Index (RSBI) were the outcome measures included. Results: Seven randomized controlled trials, including 517 participants under IMV for at least 48 h, were included in the review. From a qualitative point of view, a significant increase in MIP and a significant decrease in RSBI were found in the intervention group during the analysis. However, weaning success was the same between the intervention and control groups. No significant association was found between weaning success and the increase of MIP or the decrease of RSBI. Furthermore, it could not be demonstrated that a positive change in MIP or RSBI would increase the weaning success rates. Conclusions: From a qualitative point of view, IMT is effective in increasing MIP and decreasing RSBI. However, IMT has no significant impact on weaning success. Further research is recommended to analyze the effect of IMT on weaning success.https://www.mdpi.com/2411-5142/10/2/111inspiratory muscle trainingmechanical ventilationweaning successmaximum inspiratory pressurerapid shallow breathing indexcritical care
spellingShingle José Luís Alonso-Pérez
Víctor Riquelme-Aguado
Daniel Rodríguez-Prieto
Alejandro López-Mejías
Carlos Romero-Morales
Giacomo Rossettini
Jorge Hugo Villafañe
Inspiratory Muscle Training and Its Impact on Weaning Success in Mechanically Ventilated ICU Patients: A Systematic Review
Journal of Functional Morphology and Kinesiology
inspiratory muscle training
mechanical ventilation
weaning success
maximum inspiratory pressure
rapid shallow breathing index
critical care
title Inspiratory Muscle Training and Its Impact on Weaning Success in Mechanically Ventilated ICU Patients: A Systematic Review
title_full Inspiratory Muscle Training and Its Impact on Weaning Success in Mechanically Ventilated ICU Patients: A Systematic Review
title_fullStr Inspiratory Muscle Training and Its Impact on Weaning Success in Mechanically Ventilated ICU Patients: A Systematic Review
title_full_unstemmed Inspiratory Muscle Training and Its Impact on Weaning Success in Mechanically Ventilated ICU Patients: A Systematic Review
title_short Inspiratory Muscle Training and Its Impact on Weaning Success in Mechanically Ventilated ICU Patients: A Systematic Review
title_sort inspiratory muscle training and its impact on weaning success in mechanically ventilated icu patients a systematic review
topic inspiratory muscle training
mechanical ventilation
weaning success
maximum inspiratory pressure
rapid shallow breathing index
critical care
url https://www.mdpi.com/2411-5142/10/2/111
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