Usefulness of gel immersion endoscopy for endoscopic resection in stomachs with residue

Background and Aims: EMR and endoscopic submucosal dissection are widely used for treating intramucosal gastric neoplasms. However, securing a clear visual field in a stomach with residue is challenging. In this article, we present 2 cases in which tumors were endoscopically resected by securing the...

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Main Authors: Hiroki Hayashi, MD, Yuji Ino, MD, Chihiro Iwashita, MD, PhD, Mio Sakaguchi, MD, Yoshimasa Miura, MD, PhD, Edward J. Despott, MD, FRCP, FEBGH, FASGE, FJGES, FESGE, MD (Res), Tomonori Yano, MD, PhD, Hironori Yamamoto, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:VideoGIE
Online Access:http://www.sciencedirect.com/science/article/pii/S2468448125000980
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author Hiroki Hayashi, MD
Yuji Ino, MD
Chihiro Iwashita, MD, PhD
Mio Sakaguchi, MD
Yoshimasa Miura, MD, PhD
Edward J. Despott, MD, FRCP, FEBGH, FASGE, FJGES, FESGE, MD (Res)
Tomonori Yano, MD, PhD
Hironori Yamamoto, MD, PhD
author_facet Hiroki Hayashi, MD
Yuji Ino, MD
Chihiro Iwashita, MD, PhD
Mio Sakaguchi, MD
Yoshimasa Miura, MD, PhD
Edward J. Despott, MD, FRCP, FEBGH, FASGE, FJGES, FESGE, MD (Res)
Tomonori Yano, MD, PhD
Hironori Yamamoto, MD, PhD
author_sort Hiroki Hayashi, MD
collection DOAJ
description Background and Aims: EMR and endoscopic submucosal dissection are widely used for treating intramucosal gastric neoplasms. However, securing a clear visual field in a stomach with residue is challenging. In this article, we present 2 cases in which tumors were endoscopically resected by securing the visual field using the gel immersion method in remnant stomachs after proximal gastrectomy with residue. Methods: The gel immersion method is a technique in which a transparent, viscous gel is injected into the lumen to secure the visual field. The viscous gel displaces blood and residue, allowing for a clear view. Therefore, we could perform efficient endoscopic procedures calmly. We also used the dedicated valve to add the gel while we inserted devices through its accessory channel. Results: In both cases, the gel immersion method successfully displaced food residue, providing a clear visual field and enabling precise mucosal incision and resection. In the first case, we achieved en bloc resection in a 71-year-old man with a 5-mm adenoma by using gel immersion EMR. In the second case, a 74-year-old man with a 12-mm intramucosal adenocarcinoma underwent gel immersion endoscopic submucosal dissection, which facilitated an accurate incision line and effective coagulation. Both patients had negative resection margins, and no adverse events were observed. Conclusions: The gel immersion method effectively improved visualization in a stomach with residue, enhancing the safety and precision of endoscopic resection.
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spelling doaj-art-baadaf57473c4868b3279eb4cb1a2a3c2025-08-20T03:03:49ZengElsevierVideoGIE2468-44812025-09-0110946947410.1016/j.vgie.2025.03.040Usefulness of gel immersion endoscopy for endoscopic resection in stomachs with residueHiroki Hayashi, MD0Yuji Ino, MD1Chihiro Iwashita, MD, PhD2Mio Sakaguchi, MD3Yoshimasa Miura, MD, PhD4Edward J. Despott, MD, FRCP, FEBGH, FASGE, FJGES, FESGE, MD (Res)5Tomonori Yano, MD, PhD6Hironori Yamamoto, MD, PhD7Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, JapanDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, JapanDepartment of Gastroenterology and Hepatology, Mie University, Mie, JapanDepartment of Diagnostic Pathology, Jichi Medical University, Tochigi, JapanDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanRoyal Free Unit for Endoscopy, The Royal Free Hospital and UCL Institute for Liver and Digestive Health, London, United KingdomDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan; Corresponding author: Tomonori Yano, MD, PhD, Department of Medicine, Division of Gastroenterology, Jichi Medical, University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan.Department of Endoscopic Research and International Education funded by FUJIFILM Medical Co, Ltd, Jichi Medical University, Tochigi, JapanBackground and Aims: EMR and endoscopic submucosal dissection are widely used for treating intramucosal gastric neoplasms. However, securing a clear visual field in a stomach with residue is challenging. In this article, we present 2 cases in which tumors were endoscopically resected by securing the visual field using the gel immersion method in remnant stomachs after proximal gastrectomy with residue. Methods: The gel immersion method is a technique in which a transparent, viscous gel is injected into the lumen to secure the visual field. The viscous gel displaces blood and residue, allowing for a clear view. Therefore, we could perform efficient endoscopic procedures calmly. We also used the dedicated valve to add the gel while we inserted devices through its accessory channel. Results: In both cases, the gel immersion method successfully displaced food residue, providing a clear visual field and enabling precise mucosal incision and resection. In the first case, we achieved en bloc resection in a 71-year-old man with a 5-mm adenoma by using gel immersion EMR. In the second case, a 74-year-old man with a 12-mm intramucosal adenocarcinoma underwent gel immersion endoscopic submucosal dissection, which facilitated an accurate incision line and effective coagulation. Both patients had negative resection margins, and no adverse events were observed. Conclusions: The gel immersion method effectively improved visualization in a stomach with residue, enhancing the safety and precision of endoscopic resection.http://www.sciencedirect.com/science/article/pii/S2468448125000980
spellingShingle Hiroki Hayashi, MD
Yuji Ino, MD
Chihiro Iwashita, MD, PhD
Mio Sakaguchi, MD
Yoshimasa Miura, MD, PhD
Edward J. Despott, MD, FRCP, FEBGH, FASGE, FJGES, FESGE, MD (Res)
Tomonori Yano, MD, PhD
Hironori Yamamoto, MD, PhD
Usefulness of gel immersion endoscopy for endoscopic resection in stomachs with residue
VideoGIE
title Usefulness of gel immersion endoscopy for endoscopic resection in stomachs with residue
title_full Usefulness of gel immersion endoscopy for endoscopic resection in stomachs with residue
title_fullStr Usefulness of gel immersion endoscopy for endoscopic resection in stomachs with residue
title_full_unstemmed Usefulness of gel immersion endoscopy for endoscopic resection in stomachs with residue
title_short Usefulness of gel immersion endoscopy for endoscopic resection in stomachs with residue
title_sort usefulness of gel immersion endoscopy for endoscopic resection in stomachs with residue
url http://www.sciencedirect.com/science/article/pii/S2468448125000980
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