Hereditary Angioedema: Three Cases Report, Members of the Same Family
Background: This current clinical case report highlights three cases of Hereditary angioedema (HAE) patients who are all members of the same family (father and his two daughters). The father has C1–INH deficiency, while his daughters have low C1–INH levels: the first possesses only 10% function and...
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| Format: | Article |
| Language: | English |
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Lithuanian University of Health Sciences, Faculty of Odontology
2010-01-01
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| Series: | eJournal of Oral Maxillofacial Research |
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| Online Access: | http://www.ejomr.org/JOMR/archives/2010/1/e9/e9ht.pdf |
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| author | Alexandros Kolokotronis Paraskevi Tsirevelou Apostolos Matiakis Mattheos Papamanthos Haralambos Skoulakis |
| author_facet | Alexandros Kolokotronis Paraskevi Tsirevelou Apostolos Matiakis Mattheos Papamanthos Haralambos Skoulakis |
| author_sort | Alexandros Kolokotronis |
| collection | DOAJ |
| description | Background: This current clinical case report highlights three cases of Hereditary angioedema (HAE) patients who are all members of the same family (father and his two daughters). The father has C1–INH deficiency, while his daughters have low C1–INH levels: the first possesses only 10% function and the second has low C1–INH level with 0% function. Of note, the second daughter was discovered to have HAE at the age of 2, thus making her the youngest known HAE case report in the English literature.Methods: Assess the efficacy of administration of C1-INH before dental operation as regards the prevention of HAE episode, when total or partial C1-INH deficiency exists.Results: Acute angioedema leading to laryngeal oedema is a possibly fatal complication for HAE patients undergoing dental procedures. Use of both short-term and long-term HAE prophylaxis prior to dental operations might be life saving for those patients.Conclusions: Prevention and early recognition of potential laryngeal oedema that can occur as a complication of dental procedures may be lifesaving for HAE patients. |
| format | Article |
| id | doaj-art-baa7ac9d563b4562b1d881dff6b47cf0 |
| institution | DOAJ |
| issn | 2029-283X |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Lithuanian University of Health Sciences, Faculty of Odontology |
| record_format | Article |
| series | eJournal of Oral Maxillofacial Research |
| spelling | doaj-art-baa7ac9d563b4562b1d881dff6b47cf02025-08-20T02:51:24ZengLithuanian University of Health Sciences, Faculty of OdontologyeJournal of Oral Maxillofacial Research2029-283X2010-01-0111e9Hereditary Angioedema: Three Cases Report, Members of the Same FamilyAlexandros KolokotronisParaskevi TsirevelouApostolos MatiakisMattheos PapamanthosHaralambos SkoulakisBackground: This current clinical case report highlights three cases of Hereditary angioedema (HAE) patients who are all members of the same family (father and his two daughters). The father has C1–INH deficiency, while his daughters have low C1–INH levels: the first possesses only 10% function and the second has low C1–INH level with 0% function. Of note, the second daughter was discovered to have HAE at the age of 2, thus making her the youngest known HAE case report in the English literature.Methods: Assess the efficacy of administration of C1-INH before dental operation as regards the prevention of HAE episode, when total or partial C1-INH deficiency exists.Results: Acute angioedema leading to laryngeal oedema is a possibly fatal complication for HAE patients undergoing dental procedures. Use of both short-term and long-term HAE prophylaxis prior to dental operations might be life saving for those patients.Conclusions: Prevention and early recognition of potential laryngeal oedema that can occur as a complication of dental procedures may be lifesaving for HAE patients.http://www.ejomr.org/JOMR/archives/2010/1/e9/e9ht.pdfhereditary angioedemalaryngeal edemaoral surgical procedureoperative dentistrytooth extraction |
| spellingShingle | Alexandros Kolokotronis Paraskevi Tsirevelou Apostolos Matiakis Mattheos Papamanthos Haralambos Skoulakis Hereditary Angioedema: Three Cases Report, Members of the Same Family eJournal of Oral Maxillofacial Research hereditary angioedema laryngeal edema oral surgical procedure operative dentistry tooth extraction |
| title | Hereditary Angioedema: Three Cases Report, Members of the Same Family |
| title_full | Hereditary Angioedema: Three Cases Report, Members of the Same Family |
| title_fullStr | Hereditary Angioedema: Three Cases Report, Members of the Same Family |
| title_full_unstemmed | Hereditary Angioedema: Three Cases Report, Members of the Same Family |
| title_short | Hereditary Angioedema: Three Cases Report, Members of the Same Family |
| title_sort | hereditary angioedema three cases report members of the same family |
| topic | hereditary angioedema laryngeal edema oral surgical procedure operative dentistry tooth extraction |
| url | http://www.ejomr.org/JOMR/archives/2010/1/e9/e9ht.pdf |
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