The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19
Introduction. COVID-19, an epidemic of coronavirus infection, has become a major global threat. The coronavirus mainly targets the human respiratory system, followed by cytokine storm, and altered immune responses associated with disease progression and adverse outcomes. Sumac and pomegranate juice...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2022/6850342 |
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| author | Fatemeh Forouzanfar Mohammadreza Ahmadpoor Mostafa Moshirian Farahi Ali Hadianfar Amirhossein Sahebkar Habibollah Esmaily Mohsen Nematy Hassan Rakhshandeh |
| author_facet | Fatemeh Forouzanfar Mohammadreza Ahmadpoor Mostafa Moshirian Farahi Ali Hadianfar Amirhossein Sahebkar Habibollah Esmaily Mohsen Nematy Hassan Rakhshandeh |
| author_sort | Fatemeh Forouzanfar |
| collection | DOAJ |
| description | Introduction. COVID-19, an epidemic of coronavirus infection, has become a major global threat. The coronavirus mainly targets the human respiratory system, followed by cytokine storm, and altered immune responses associated with disease progression and adverse outcomes. Sumac and pomegranate juice are rich in bioactive compounds, which potentially have antiviral activities. This study is aimed at investigating the effect of a diet based on the use of sumac and pomegranate juice on the treatment of outpatients with COVID-19. Methods. In this study, 182 outpatients with COVID-19 were randomly divided into two groups receiving a diet containing pomegranate juice and sumac along with standard treatment and the control group (group 2) receiving standard treatment. Results. Consumption of a diet containing pomegranate juice and sumac in outpatients with COVID-19, who were receiving standard-of-care treatment, led to a significant decrease in fever, chills, cough, weakness, smell and taste disorders, shortness of breath, diarrhea, nausea and vomiting, and abdominal pain compared with outpatients with COVID-19 who received only standard treatment. Conclusion. Clinical trials of outpatients have limitations such as patients’ resilience to post-COVID-19 follow-up. However, the use of pomegranate juice and sumac can be efficacious in reducing COVID-19 symptoms. This trial is registered with IRCT20190406043175N3. |
| format | Article |
| id | doaj-art-baa3f3b7c6fa465b8688954ff72a58ec |
| institution | OA Journals |
| issn | 1466-1861 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-baa3f3b7c6fa465b8688954ff72a58ec2025-08-20T02:19:21ZengWileyMediators of Inflammation1466-18612022-01-01202210.1155/2022/6850342The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19Fatemeh Forouzanfar0Mohammadreza Ahmadpoor1Mostafa Moshirian Farahi2Ali Hadianfar3Amirhossein Sahebkar4Habibollah Esmaily5Mohsen Nematy6Hassan Rakhshandeh7Neuroscience Research CenterDepartment of Persian MedicinePharmacological Research Center of Medicinal PlantsStudent Research CommitteeApplied Biomedical Research CenterSocial Determinants of Health Research CenterDepartment of NutritionPharmacological Research Center of Medicinal PlantsIntroduction. COVID-19, an epidemic of coronavirus infection, has become a major global threat. The coronavirus mainly targets the human respiratory system, followed by cytokine storm, and altered immune responses associated with disease progression and adverse outcomes. Sumac and pomegranate juice are rich in bioactive compounds, which potentially have antiviral activities. This study is aimed at investigating the effect of a diet based on the use of sumac and pomegranate juice on the treatment of outpatients with COVID-19. Methods. In this study, 182 outpatients with COVID-19 were randomly divided into two groups receiving a diet containing pomegranate juice and sumac along with standard treatment and the control group (group 2) receiving standard treatment. Results. Consumption of a diet containing pomegranate juice and sumac in outpatients with COVID-19, who were receiving standard-of-care treatment, led to a significant decrease in fever, chills, cough, weakness, smell and taste disorders, shortness of breath, diarrhea, nausea and vomiting, and abdominal pain compared with outpatients with COVID-19 who received only standard treatment. Conclusion. Clinical trials of outpatients have limitations such as patients’ resilience to post-COVID-19 follow-up. However, the use of pomegranate juice and sumac can be efficacious in reducing COVID-19 symptoms. This trial is registered with IRCT20190406043175N3.http://dx.doi.org/10.1155/2022/6850342 |
| spellingShingle | Fatemeh Forouzanfar Mohammadreza Ahmadpoor Mostafa Moshirian Farahi Ali Hadianfar Amirhossein Sahebkar Habibollah Esmaily Mohsen Nematy Hassan Rakhshandeh The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19 Mediators of Inflammation |
| title | The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19 |
| title_full | The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19 |
| title_fullStr | The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19 |
| title_full_unstemmed | The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19 |
| title_short | The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19 |
| title_sort | effect of pomegranate juice and sumac consumption in the treatment of outpatients with covid 19 |
| url | http://dx.doi.org/10.1155/2022/6850342 |
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