Shifts in growth strategies reflect tradeoffs in cellular economics
Abstract The growth rate‐dependent regulation of cell size, ribosomal content, and metabolic efficiency follows a common pattern in unicellular organisms: with increasing growth rates, cell size and ribosomal content increase and a shift to energetically inefficient metabolism takes place. The latte...
Saved in:
| Main Authors: | Douwe Molenaar, Rogier van Berlo, Dick de Ridder, Bas Teusink |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2009-11-01
|
| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb.2009.82 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Overflow metabolism originates from growth optimization and cell heterogeneity
by: Xin Wang
Published: (2025-06-01) -
A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus
by: Nabia Shahreen, et al.
Published: (2025-01-01) -
Allosteric regulation of pyruvate kinase enables efficient and robust gluconeogenesis by preventing metabolic conflicts and carbon overflow
by: Fukang She, et al.
Published: (2025-02-01) -
Unraveling the connection: M2 macrophage polarization and cancer metabolism
by: José Daniel Moreno-Ocampo, et al.
Published: (2025-08-01) -
Glucose metabolism and endometrium decidualization
by: Yunfei Huang, et al.
Published: (2025-02-01)