The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis.

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis.

<h4>Background</h4>Delay in receiving treatment for uncomplicated malaria (UM) is often reported to increase the risk of developing severe malaria (SM), but access to treatment remains low in most high-burden areas. Understanding the contribution of treatment delay on progression to seve...

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Main Authors: Andria Mousa, Abdullah Al-Taiar, Nicholas M Anstey, Cyril Badaut, Bridget E Barber, Quique Bassat, Joseph D Challenger, Aubrey J Cunnington, Dibyadyuti Datta, Chris Drakeley, Azra C Ghani, Victor R Gordeuk, Matthew J Grigg, Pierre Hugo, Chandy C John, Alfredo Mayor, Florence Migot-Nabias, Robert O Opoka, Geoffrey Pasvol, Claire Rees, Hugh Reyburn, Eleanor M Riley, Binal N Shah, Antonio Sitoe, Colin J Sutherland, Philip E Thuma, Stefan A Unger, Firmine Viwami, Michael Walther, Christopher J M Whitty, Timothy William, Lucy C Okell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1003359
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