COVID-19 pandemic in low-risk pregnant women in 2020-2022: disease confounders and clinical characteristics
Aim. To identify confounders and clinical symptoms of COVID-19 in low-risk pregnant women during the pandemics from 2020 to 2022.Materials and Methods. The study included pregnant women with COVID-19: 1) those who have been admitted in October-December 2020 (n = 163); 2) those who have been admitted...
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| Format: | Article |
| Language: | Russian |
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Kemerovo State Medical University
2023-04-01
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| Series: | Фундаментальная и клиническая медицина |
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| Online Access: | https://fcm.kemsmu.ru/jour/article/view/674 |
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| author | T. E. Belokrinitskaya N. I. Frolova K. A. Kargina E. A. Shametova M. I. Chuprova K. A. Rodionova |
| author_facet | T. E. Belokrinitskaya N. I. Frolova K. A. Kargina E. A. Shametova M. I. Chuprova K. A. Rodionova |
| author_sort | T. E. Belokrinitskaya |
| collection | DOAJ |
| description | Aim. To identify confounders and clinical symptoms of COVID-19 in low-risk pregnant women during the pandemics from 2020 to 2022.Materials and Methods. The study included pregnant women with COVID-19: 1) those who have been admitted in October-December 2020 (n = 163); 2) those who have been admitted in May-August 2021 (n = 158); 3) those who have been admitted in January-February 2022 (n = 160). Patients in all groups were in the 3st trimester of gestation and were comparable in age (18–35 years), socioeconomic status, parity, body mass index, and had no established risk factors for COVID-19.Results. Iron deficiency anemia, tobacco smoking, and belonging to the East Asian ethnic group were recognized as reliable confounders for COVID-19 in pregnant women. In the 1st year of the pandemic, the most common symptoms were: loss of smell/taste (87.7%), somnolence (68,7%), and shortness of breath (68.1%). In the 2nd pandemic year, SARS-CoV-2 Delta variant more frequently resulted in fever above 38°C (19.6% vs 7.4%), pneumonia (61.4% vs 21.4%), respiratory failure (17.7% vs 4.9%), admission to intensive care unit (11.4% vs 6.4%), and invasive mechanical ventilation (1.89% vs 0). Symptoms of COVID-19 in the 3rd year of the pandemic were similar to those observed in seasonal acute respiratory viral infections: runny nose (66.7%) and cough (54.4%), whereas the cases of pneumonia were rare (3.8%).Conclusion. Among the most reliable confounders of COVID-19 in pregnant women without any risk factors in the 3rd trimester of gestation are iron deficiency anemia, tobacco smoking, and belonging to the East Asian ethnic group. Each SARS-CoV-2 variant provoked vastly different symptoms. |
| format | Article |
| id | doaj-art-ba827fc1e1e0410ab6be7ddd2c8ca459 |
| institution | Kabale University |
| issn | 2500-0764 2542-0941 |
| language | Russian |
| publishDate | 2023-04-01 |
| publisher | Kemerovo State Medical University |
| record_format | Article |
| series | Фундаментальная и клиническая медицина |
| spelling | doaj-art-ba827fc1e1e0410ab6be7ddd2c8ca4592025-08-20T03:42:37ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412023-04-0181324210.23946/2500-0764-2023-8-1-32-42351COVID-19 pandemic in low-risk pregnant women in 2020-2022: disease confounders and clinical characteristicsT. E. Belokrinitskaya0N. I. Frolova1K. A. Kargina2E. A. Shametova3M. I. Chuprova4K. A. Rodionova5Chita State Medical AcademyChita State Medical AcademyChita State Medical AcademyChita State Medical AcademyChita State Medical AcademyChita State Medical AcademyAim. To identify confounders and clinical symptoms of COVID-19 in low-risk pregnant women during the pandemics from 2020 to 2022.Materials and Methods. The study included pregnant women with COVID-19: 1) those who have been admitted in October-December 2020 (n = 163); 2) those who have been admitted in May-August 2021 (n = 158); 3) those who have been admitted in January-February 2022 (n = 160). Patients in all groups were in the 3st trimester of gestation and were comparable in age (18–35 years), socioeconomic status, parity, body mass index, and had no established risk factors for COVID-19.Results. Iron deficiency anemia, tobacco smoking, and belonging to the East Asian ethnic group were recognized as reliable confounders for COVID-19 in pregnant women. In the 1st year of the pandemic, the most common symptoms were: loss of smell/taste (87.7%), somnolence (68,7%), and shortness of breath (68.1%). In the 2nd pandemic year, SARS-CoV-2 Delta variant more frequently resulted in fever above 38°C (19.6% vs 7.4%), pneumonia (61.4% vs 21.4%), respiratory failure (17.7% vs 4.9%), admission to intensive care unit (11.4% vs 6.4%), and invasive mechanical ventilation (1.89% vs 0). Symptoms of COVID-19 in the 3rd year of the pandemic were similar to those observed in seasonal acute respiratory viral infections: runny nose (66.7%) and cough (54.4%), whereas the cases of pneumonia were rare (3.8%).Conclusion. Among the most reliable confounders of COVID-19 in pregnant women without any risk factors in the 3rd trimester of gestation are iron deficiency anemia, tobacco smoking, and belonging to the East Asian ethnic group. Each SARS-CoV-2 variant provoked vastly different symptoms.https://fcm.kemsmu.ru/jour/article/view/674pregnancycovid-19clinical picturepneumoniarisk factors |
| spellingShingle | T. E. Belokrinitskaya N. I. Frolova K. A. Kargina E. A. Shametova M. I. Chuprova K. A. Rodionova COVID-19 pandemic in low-risk pregnant women in 2020-2022: disease confounders and clinical characteristics Фундаментальная и клиническая медицина pregnancy covid-19 clinical picture pneumonia risk factors |
| title | COVID-19 pandemic in low-risk pregnant women in 2020-2022: disease confounders and clinical characteristics |
| title_full | COVID-19 pandemic in low-risk pregnant women in 2020-2022: disease confounders and clinical characteristics |
| title_fullStr | COVID-19 pandemic in low-risk pregnant women in 2020-2022: disease confounders and clinical characteristics |
| title_full_unstemmed | COVID-19 pandemic in low-risk pregnant women in 2020-2022: disease confounders and clinical characteristics |
| title_short | COVID-19 pandemic in low-risk pregnant women in 2020-2022: disease confounders and clinical characteristics |
| title_sort | covid 19 pandemic in low risk pregnant women in 2020 2022 disease confounders and clinical characteristics |
| topic | pregnancy covid-19 clinical picture pneumonia risk factors |
| url | https://fcm.kemsmu.ru/jour/article/view/674 |
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