Yucasin Alleviates Aluminum Toxicity Associated with Regulating Reactive Oxygen Species Homeostasis in Tomato Seedlings
The phytotoxicity of aluminum (Al) to plants is well known. Auxin accumulation and reactive oxygen species (ROS) burst induced by Al toxicity are the key factors in root growth inhibition. Yucasin, an auxin synthesis inhibitor, effectively ameliorates Al phytotoxicity in tomato seedlings. However, t...
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MDPI AG
2025-05-01
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| Series: | Toxics |
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| author | Huabin Liu Chuangyang Bai Jiahui Cai Yue Wu Changwei Zhu |
| author_facet | Huabin Liu Chuangyang Bai Jiahui Cai Yue Wu Changwei Zhu |
| author_sort | Huabin Liu |
| collection | DOAJ |
| description | The phytotoxicity of aluminum (Al) to plants is well known. Auxin accumulation and reactive oxygen species (ROS) burst induced by Al toxicity are the key factors in root growth inhibition. Yucasin, an auxin synthesis inhibitor, effectively ameliorates Al phytotoxicity in tomato seedlings. However, the physiological mechanisms by which yucasin alleviates Al phytotoxicity in tomatoes remain elusive. Here, we examined the regulatory mechanisms of yucasin involved in tomato seedling growth under Al conditions through phenotypic, plant physiology analysis, and cellular experiments. Exogenous indole-3-acetic acid (IAA) application increased Al accumulation in tomato seedling roots, while yucasin decreased Al accumulation. Yucasin application reduced Al-induced ROS accumulation, lipid peroxidation, and cell death, enhanced root viability, and promoted tomato seedling root growth. Further, yucasin enhanced the antioxidant enzyme activities of superoxide dismutase, catalase, and peroxidase in plants under Al conditions. The results suggest that yucasin improves the scavenging capacity of ROS by maintaining the activities of antioxidative enzymes. This study elucidates the physiological mechanism by which yucasin alleviates Al phytotoxicity, highlighting its potential to enhance plant tolerance under acidic Al conditions. |
| format | Article |
| id | doaj-art-ba82398fcf7244b29eeb13d0e13ca6a3 |
| institution | Kabale University |
| issn | 2305-6304 |
| language | English |
| publishDate | 2025-05-01 |
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| series | Toxics |
| spelling | doaj-art-ba82398fcf7244b29eeb13d0e13ca6a32025-08-20T03:47:54ZengMDPI AGToxics2305-63042025-05-0113540610.3390/toxics13050406Yucasin Alleviates Aluminum Toxicity Associated with Regulating Reactive Oxygen Species Homeostasis in Tomato SeedlingsHuabin Liu0Chuangyang Bai1Jiahui Cai2Yue Wu3Changwei Zhu4College of Biomedicine and Health, Anhui Science and Technology University, Chuzhou 233100, ChinaCollege of Biomedicine and Health, Anhui Science and Technology University, Chuzhou 233100, ChinaCollege of Biomedicine and Health, Anhui Science and Technology University, Chuzhou 233100, ChinaCollege of Biomedicine and Health, Anhui Science and Technology University, Chuzhou 233100, ChinaCollege of Biomedicine and Health, Anhui Science and Technology University, Chuzhou 233100, ChinaThe phytotoxicity of aluminum (Al) to plants is well known. Auxin accumulation and reactive oxygen species (ROS) burst induced by Al toxicity are the key factors in root growth inhibition. Yucasin, an auxin synthesis inhibitor, effectively ameliorates Al phytotoxicity in tomato seedlings. However, the physiological mechanisms by which yucasin alleviates Al phytotoxicity in tomatoes remain elusive. Here, we examined the regulatory mechanisms of yucasin involved in tomato seedling growth under Al conditions through phenotypic, plant physiology analysis, and cellular experiments. Exogenous indole-3-acetic acid (IAA) application increased Al accumulation in tomato seedling roots, while yucasin decreased Al accumulation. Yucasin application reduced Al-induced ROS accumulation, lipid peroxidation, and cell death, enhanced root viability, and promoted tomato seedling root growth. Further, yucasin enhanced the antioxidant enzyme activities of superoxide dismutase, catalase, and peroxidase in plants under Al conditions. The results suggest that yucasin improves the scavenging capacity of ROS by maintaining the activities of antioxidative enzymes. This study elucidates the physiological mechanism by which yucasin alleviates Al phytotoxicity, highlighting its potential to enhance plant tolerance under acidic Al conditions.https://www.mdpi.com/2305-6304/13/5/406aluminum toxicityyucasinROS homeostasisantioxidant systemtomato |
| spellingShingle | Huabin Liu Chuangyang Bai Jiahui Cai Yue Wu Changwei Zhu Yucasin Alleviates Aluminum Toxicity Associated with Regulating Reactive Oxygen Species Homeostasis in Tomato Seedlings Toxics aluminum toxicity yucasin ROS homeostasis antioxidant system tomato |
| title | Yucasin Alleviates Aluminum Toxicity Associated with Regulating Reactive Oxygen Species Homeostasis in Tomato Seedlings |
| title_full | Yucasin Alleviates Aluminum Toxicity Associated with Regulating Reactive Oxygen Species Homeostasis in Tomato Seedlings |
| title_fullStr | Yucasin Alleviates Aluminum Toxicity Associated with Regulating Reactive Oxygen Species Homeostasis in Tomato Seedlings |
| title_full_unstemmed | Yucasin Alleviates Aluminum Toxicity Associated with Regulating Reactive Oxygen Species Homeostasis in Tomato Seedlings |
| title_short | Yucasin Alleviates Aluminum Toxicity Associated with Regulating Reactive Oxygen Species Homeostasis in Tomato Seedlings |
| title_sort | yucasin alleviates aluminum toxicity associated with regulating reactive oxygen species homeostasis in tomato seedlings |
| topic | aluminum toxicity yucasin ROS homeostasis antioxidant system tomato |
| url | https://www.mdpi.com/2305-6304/13/5/406 |
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