Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related Disease
Skin is a vital barrier for the human body, protecting against external environmental influences and maintaining internal homeostasis. In addition, an imbalance of oxidative stress and antioxidant mechanisms can lead to skin-related diseases. Thus, for treating skin-related diseases, antioxidant the...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-12-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/14/1/27 |
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| author | Yi Xue Tao Wang Ji-Peng Liu Qi Chen Xiao-Long Dai Min Su Yu-Hang Cheng Cheng-Chao Chu Yun-Qing Ren |
| author_facet | Yi Xue Tao Wang Ji-Peng Liu Qi Chen Xiao-Long Dai Min Su Yu-Hang Cheng Cheng-Chao Chu Yun-Qing Ren |
| author_sort | Yi Xue |
| collection | DOAJ |
| description | Skin is a vital barrier for the human body, protecting against external environmental influences and maintaining internal homeostasis. In addition, an imbalance of oxidative stress and antioxidant mechanisms can lead to skin-related diseases. Thus, for treating skin-related diseases, antioxidant therapy may be an important strategy to alleviate these symptoms. However, traditional drug therapies have limitations in treating these conditions, such as lack of lasting effect and insufficient skin permeability. Recently, nano-antioxidants, with their good permeability, sustained-release ability, multifunctionality, and other beneficial characteristics, have showed their advances in the exploration of skin-related diseases from research on safe therapies to clinical practice. Hereby, we review the latest research and advancements in nano-antioxidants for skin-related diseases. We categorize skin-related diseases into four main groups: skin inflammatory diseases, skin damage caused by ultraviolet rays, skin wound healing, and other skin-related conditions. Additionally, we summarize the prospects and potential future directions for nano-antioxidant drugs in treating skin-related diseases. |
| format | Article |
| id | doaj-art-ba7e3d1150e24d97b9db6284f27d835c |
| institution | Kabale University |
| issn | 2076-3921 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj-art-ba7e3d1150e24d97b9db6284f27d835c2025-01-24T13:19:12ZengMDPI AGAntioxidants2076-39212024-12-011412710.3390/antiox14010027Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related DiseaseYi Xue0Tao Wang1Ji-Peng Liu2Qi Chen3Xiao-Long Dai4Min Su5Yu-Hang Cheng6Cheng-Chao Chu7Yun-Qing Ren8Department of Dermatology, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310003, ChinaDepartment of Dermatology, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310003, ChinaDepartment of Dermatology, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310003, ChinaDepartment of Dermatology, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310003, ChinaDepartment of Dermatology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, ChinaDepartment of Pharmacy, Xiamen Medical College, Xiamen 361023, ChinaXiamen University Affiliated Xiamen Eye Center, Eye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen 361102, ChinaXiamen University Affiliated Xiamen Eye Center, Eye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen 361102, ChinaDepartment of Dermatology, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310003, ChinaSkin is a vital barrier for the human body, protecting against external environmental influences and maintaining internal homeostasis. In addition, an imbalance of oxidative stress and antioxidant mechanisms can lead to skin-related diseases. Thus, for treating skin-related diseases, antioxidant therapy may be an important strategy to alleviate these symptoms. However, traditional drug therapies have limitations in treating these conditions, such as lack of lasting effect and insufficient skin permeability. Recently, nano-antioxidants, with their good permeability, sustained-release ability, multifunctionality, and other beneficial characteristics, have showed their advances in the exploration of skin-related diseases from research on safe therapies to clinical practice. Hereby, we review the latest research and advancements in nano-antioxidants for skin-related diseases. We categorize skin-related diseases into four main groups: skin inflammatory diseases, skin damage caused by ultraviolet rays, skin wound healing, and other skin-related conditions. Additionally, we summarize the prospects and potential future directions for nano-antioxidant drugs in treating skin-related diseases.https://www.mdpi.com/2076-3921/14/1/27skinnano-antioxidantsROSnanomedicine |
| spellingShingle | Yi Xue Tao Wang Ji-Peng Liu Qi Chen Xiao-Long Dai Min Su Yu-Hang Cheng Cheng-Chao Chu Yun-Qing Ren Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related Disease Antioxidants skin nano-antioxidants ROS nanomedicine |
| title | Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related Disease |
| title_full | Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related Disease |
| title_fullStr | Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related Disease |
| title_full_unstemmed | Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related Disease |
| title_short | Recent Trends in the Development and Application of Nano-Antioxidants for Skin-Related Disease |
| title_sort | recent trends in the development and application of nano antioxidants for skin related disease |
| topic | skin nano-antioxidants ROS nanomedicine |
| url | https://www.mdpi.com/2076-3921/14/1/27 |
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