Coronavirus nucleocapsid protein enhances the binding of p-PKCα to RACK1: Implications for inhibition of nucleocytoplasmic trafficking and suppression of the innate immune response.
The hallmark of coronavirus infection lies in its ability to evade host immune defenses, a process intricately linked to the nuclear entry of transcription factors crucial for initiating the expression of antiviral genes. Central to this evasion strategy is the manipulation of the nucleocytoplasmic...
Saved in:
| Main Authors: | Wenxiang Xue, Hongyan Chu, Jiehuang Wang, Yingjie Sun, Xusheng Qiu, Cuiping Song, Lei Tan, Chan Ding, Ying Liao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-11-01
|
| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1012097 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Coronavirus endoribonuclease nsp15 suppresses host protein synthesis and evades PKR-eIF2α-mediated translation shutoff to ensure viral protein synthesis.
by: Xiaoqian Gong, et al.
Published: (2025-03-01) -
UGDH Lactylation Aggravates Osteoarthritis by Suppressing Glycosaminoglycan Synthesis and Orchestrating Nucleocytoplasmic Transport to Activate MAPK Signaling
by: Weiren Lan, et al.
Published: (2025-05-01) -
Deficient induction response in a Xenopus nucleocytoplasmic hybrid.
by: Patrick Narbonne, et al.
Published: (2011-11-01) -
Chemokines simultaneously bind SARS-CoV-2 nucleocapsid protein RNA-binding and dimerization domains
by: Alberto Domingo López-Muñoz, et al.
Published: (2025-03-01) -
Soluble expression of nucleocapsid protein of feline coronavirus and reactivity identification of its polyclonal antibody
by: ZHANG Dan, et al.
Published: (2023-06-01)