Chemo-selective modification of cysteine residue: synthesis and application in the discovery of potential drug candidates
Chemo-select modification of peptides, targeting a handful of the most reactive proteinogenic amino acids (AAs), is gradually utilized to address the medical needs of peptide drugs and biopharmaceuticals. Cysteine (Cys), one of the less abundant AAs in many biological proteins, plays a vital role in...
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Main Authors: | Yanyan Liao, Xuefeng Jiang |
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Format: | Article |
Language: | English |
Published: |
Open Exploration
2024-09-01
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Series: | Exploration of Drug Science |
Subjects: | |
Online Access: | https://www.explorationpub.com/uploads/Article/A100860/100860.pdf |
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