Antioxidant, Antibacterial Activities and Synergistic Effect with Antibiotics of Fruits and Stems Extracts from Styphnolobium japonicum (L.) Schott

The objective of this study was to evaluate the antioxidant and antibacterial properties of Styphnolobium japonicum (L.) Schott extracts. Results showed that the total phenols and flavonoids contents of the extracts ranged from 24.57 to 316.11 mg GAE/g and from 1.80 to 12.41μg QE/mg, respectively. E...

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Main Authors: Karima Saffidine, Fatima Zerargui, Thoraya Guemaz, Charafeddine Lameche, Farida Sahli, Abderahmane Baghiani
Format: Article
Language:English
Published: Hasan Eleroğlu 2023-02-01
Series:Turkish Journal of Agriculture: Food Science and Technology
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Online Access:http://www.agrifoodscience.com/index.php/TURJAF/article/view/5362
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author Karima Saffidine
Fatima Zerargui
Thoraya Guemaz
Charafeddine Lameche
Farida Sahli
Abderahmane Baghiani
author_facet Karima Saffidine
Fatima Zerargui
Thoraya Guemaz
Charafeddine Lameche
Farida Sahli
Abderahmane Baghiani
author_sort Karima Saffidine
collection DOAJ
description The objective of this study was to evaluate the antioxidant and antibacterial properties of Styphnolobium japonicum (L.) Schott extracts. Results showed that the total phenols and flavonoids contents of the extracts ranged from 24.57 to 316.11 mg GAE/g and from 1.80 to 12.41μg QE/mg, respectively. Ethyl acetate (EaES) and aqueous (AqES) extracts from seeds showed the highest DPPH scavenging capacity (IC50= 5.51 and 23.43 μg/mL). EaES from seeds, stem bark and fruit pod were the most active in inhibiting β-carotene oxidation. While, aqueous extracts have the ability to chelate ferrous ions. Significant antibacterial activity was obtained against Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Salmonella typhimurium, Listeria monocytogenes, Bacillus cereus and Pseudomonas aeroginosa; and inhibition zones varied between 10 to 29.5 mm. MIC and MBC ranged from 0.7–11.25 mg/mL and 5.63–22.5 mg/mL, respectively. In addition, synergistic effects were obtained, where inhibition zones varied between 7 and 50 mm. These results support the use of this species in traditional medicine in many physiological disorders and could be used where antioxidant and antibacterial are warranted.
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publisher Hasan Eleroğlu
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series Turkish Journal of Agriculture: Food Science and Technology
spelling doaj-art-ba75ecf6e4df48278d979cd404079c3c2025-08-20T02:19:26ZengHasan EleroğluTurkish Journal of Agriculture: Food Science and Technology2148-127X2023-02-0111238338910.24925/turjaf.v11i2.383-389.53624204Antioxidant, Antibacterial Activities and Synergistic Effect with Antibiotics of Fruits and Stems Extracts from Styphnolobium japonicum (L.) SchottKarima Saffidine0https://orcid.org/0000-0001-7122-961XFatima Zerargui1https://orcid.org/0000-0002-4059-3600Thoraya Guemaz2https://orcid.org/0000-0002-5074-3991Charafeddine Lameche3https://orcid.org/0000-0003-0014-4701Farida Sahli4https://orcid.org/0000-0001-9858-0530Abderahmane Baghiani5https://orcid.org/0000-0002-6881-011XLaboratory of Applied Biochemistry, Faculty of Nature and Life Sciences, Ferhat Abbas University Setif1, Setif, Algeria.Laboratory of Applied Biochemistry, Faculty of Nature and Life Sciences, Ferhat Abbas University Setif1, SetifLaboratory of Applied Biochemistry, Faculty of Nature and Life Sciences, Ferhat Abbas University Setif1, SetifDepartment of Pharmacy, Faculty of Medicine, Ferhat Abbas University Setif 1, SetifLaboratory of Bacteriology, CHU of Setif, SetifLaboratory of Applied Biochemistry, Faculty of Nature and Life Sciences, Ferhat Abbas University Setif1, SetifThe objective of this study was to evaluate the antioxidant and antibacterial properties of Styphnolobium japonicum (L.) Schott extracts. Results showed that the total phenols and flavonoids contents of the extracts ranged from 24.57 to 316.11 mg GAE/g and from 1.80 to 12.41μg QE/mg, respectively. Ethyl acetate (EaES) and aqueous (AqES) extracts from seeds showed the highest DPPH scavenging capacity (IC50= 5.51 and 23.43 μg/mL). EaES from seeds, stem bark and fruit pod were the most active in inhibiting β-carotene oxidation. While, aqueous extracts have the ability to chelate ferrous ions. Significant antibacterial activity was obtained against Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Salmonella typhimurium, Listeria monocytogenes, Bacillus cereus and Pseudomonas aeroginosa; and inhibition zones varied between 10 to 29.5 mm. MIC and MBC ranged from 0.7–11.25 mg/mL and 5.63–22.5 mg/mL, respectively. In addition, synergistic effects were obtained, where inhibition zones varied between 7 and 50 mm. These results support the use of this species in traditional medicine in many physiological disorders and could be used where antioxidant and antibacterial are warranted.http://www.agrifoodscience.com/index.php/TURJAF/article/view/5362antimicrobial activityantioxidantsflavonoidspolyphenolssophora japonica
spellingShingle Karima Saffidine
Fatima Zerargui
Thoraya Guemaz
Charafeddine Lameche
Farida Sahli
Abderahmane Baghiani
Antioxidant, Antibacterial Activities and Synergistic Effect with Antibiotics of Fruits and Stems Extracts from Styphnolobium japonicum (L.) Schott
Turkish Journal of Agriculture: Food Science and Technology
antimicrobial activity
antioxidants
flavonoids
polyphenols
sophora japonica
title Antioxidant, Antibacterial Activities and Synergistic Effect with Antibiotics of Fruits and Stems Extracts from Styphnolobium japonicum (L.) Schott
title_full Antioxidant, Antibacterial Activities and Synergistic Effect with Antibiotics of Fruits and Stems Extracts from Styphnolobium japonicum (L.) Schott
title_fullStr Antioxidant, Antibacterial Activities and Synergistic Effect with Antibiotics of Fruits and Stems Extracts from Styphnolobium japonicum (L.) Schott
title_full_unstemmed Antioxidant, Antibacterial Activities and Synergistic Effect with Antibiotics of Fruits and Stems Extracts from Styphnolobium japonicum (L.) Schott
title_short Antioxidant, Antibacterial Activities and Synergistic Effect with Antibiotics of Fruits and Stems Extracts from Styphnolobium japonicum (L.) Schott
title_sort antioxidant antibacterial activities and synergistic effect with antibiotics of fruits and stems extracts from styphnolobium japonicum l schott
topic antimicrobial activity
antioxidants
flavonoids
polyphenols
sophora japonica
url http://www.agrifoodscience.com/index.php/TURJAF/article/view/5362
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