<i>Ulva</i> Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial Design

Green seaweed is currently underused compared with other major seaweed types. Many scientists have reported applications of the green seaweed <i>Ulva</i> in various fields in recent years, which makes it a candidate for biomass production in industrial biorefineries. <i>Ulva</i&...

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Main Authors: Rizfi Fariz Pari, Uju Uju, Safrina Dyah Hardiningtyas, Wahyu Ramadhan, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Marine Drugs
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Online Access:https://www.mdpi.com/1660-3397/23/2/56
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author Rizfi Fariz Pari
Uju Uju
Safrina Dyah Hardiningtyas
Wahyu Ramadhan
Rie Wakabayashi
Masahiro Goto
Noriho Kamiya
author_facet Rizfi Fariz Pari
Uju Uju
Safrina Dyah Hardiningtyas
Wahyu Ramadhan
Rie Wakabayashi
Masahiro Goto
Noriho Kamiya
author_sort Rizfi Fariz Pari
collection DOAJ
description Green seaweed is currently underused compared with other major seaweed types. Many scientists have reported applications of the green seaweed <i>Ulva</i> in various fields in recent years, which makes it a candidate for biomass production in industrial biorefineries. <i>Ulva</i> contains a unique polysaccharide called ulvan, which is being considered for medicinal and pharmacological applications. Ulvan is a sulfated polysaccharide including rhamnose and glucuronic acid residues, which has a range of bioactivities, including immunomodulatory, antimicrobial, and anticoagulant properties. The biocompatibility of ulvan makes it a versatile candidate for biomaterial design. This review presents an in-depth analysis of the potential applications of ulvan, starting with extraction methods and structural/biological characterization and moving on to biomaterial design. We also highlight the advantages of ulvan over traditional seaweed polysaccharides such as agar, carrageenan, and alginate.
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series Marine Drugs
spelling doaj-art-ba7542e300984deca303ed00a4e5c50b2025-08-20T03:11:21ZengMDPI AGMarine Drugs1660-33972025-01-012325610.3390/md23020056<i>Ulva</i> Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial DesignRizfi Fariz Pari0Uju Uju1Safrina Dyah Hardiningtyas2Wahyu Ramadhan3Rie Wakabayashi4Masahiro Goto5Noriho Kamiya6Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka 819-0395, JapanDepartment of Aquatic Product Technology, Faculty of Fisheries and Marine Sciences, IPB University, Bogor 16680, IndonesiaDepartment of Aquatic Product Technology, Faculty of Fisheries and Marine Sciences, IPB University, Bogor 16680, IndonesiaDepartment of Aquatic Product Technology, Faculty of Fisheries and Marine Sciences, IPB University, Bogor 16680, IndonesiaDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka 819-0395, JapanDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka 819-0395, JapanDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka 819-0395, JapanGreen seaweed is currently underused compared with other major seaweed types. Many scientists have reported applications of the green seaweed <i>Ulva</i> in various fields in recent years, which makes it a candidate for biomass production in industrial biorefineries. <i>Ulva</i> contains a unique polysaccharide called ulvan, which is being considered for medicinal and pharmacological applications. Ulvan is a sulfated polysaccharide including rhamnose and glucuronic acid residues, which has a range of bioactivities, including immunomodulatory, antimicrobial, and anticoagulant properties. The biocompatibility of ulvan makes it a versatile candidate for biomaterial design. This review presents an in-depth analysis of the potential applications of ulvan, starting with extraction methods and structural/biological characterization and moving on to biomaterial design. We also highlight the advantages of ulvan over traditional seaweed polysaccharides such as agar, carrageenan, and alginate.https://www.mdpi.com/1660-3397/23/2/56cellulosegreen seaweedmarine biomaterialulvan
spellingShingle Rizfi Fariz Pari
Uju Uju
Safrina Dyah Hardiningtyas
Wahyu Ramadhan
Rie Wakabayashi
Masahiro Goto
Noriho Kamiya
<i>Ulva</i> Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial Design
Marine Drugs
cellulose
green seaweed
marine biomaterial
ulvan
title <i>Ulva</i> Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial Design
title_full <i>Ulva</i> Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial Design
title_fullStr <i>Ulva</i> Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial Design
title_full_unstemmed <i>Ulva</i> Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial Design
title_short <i>Ulva</i> Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial Design
title_sort i ulva i seaweed derived ulvan a promising marine polysaccharide as a sustainable resource for biomaterial design
topic cellulose
green seaweed
marine biomaterial
ulvan
url https://www.mdpi.com/1660-3397/23/2/56
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