A rare case of angiosarcoma presenting as pleuro-pulmonary metastasis: A case report

Angiosarcoma is an uncommon yet highly aggressive tumor originating from vascular endothelial cells, accounting for <2% of all sarcomas. Pulmonary involvement is often due to metastasis and presents with non-specific respiratory symptoms, leading to frequent misdiagnosis and delays in treatment....

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Main Authors: Abi G, Pugazhendhi S, Padamati Advytha, Nalini Jayanthi Nagesh
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2025-05-01
Series:Asian Journal of Medical Sciences
Subjects:
Online Access:https://ajmsjournal.info/index.php/AJMS/article/view/4493
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author Abi G
Pugazhendhi S
Padamati Advytha
Nalini Jayanthi Nagesh
author_facet Abi G
Pugazhendhi S
Padamati Advytha
Nalini Jayanthi Nagesh
author_sort Abi G
collection DOAJ
description Angiosarcoma is an uncommon yet highly aggressive tumor originating from vascular endothelial cells, accounting for <2% of all sarcomas. Pulmonary involvement is often due to metastasis and presents with non-specific respiratory symptoms, leading to frequent misdiagnosis and delays in treatment. We report a case of a 74-year-old male with progressive breathlessness and recurrent hemoptysis. Imaging studies revealed multiple nodular deposits in the pleura and lung parenchyma. Histopathological and immunohistochemical analyses confirmed the diagnosis of metastatic angiosarcoma. This case underscores the significance of early recognition and histopathological confirmation in patients presenting with unexplained respiratory distress. A high index of suspicion is essential for timely diagnosis and intervention.
format Article
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issn 2467-9100
2091-0576
language English
publishDate 2025-05-01
publisher Manipal College of Medical Sciences, Pokhara
record_format Article
series Asian Journal of Medical Sciences
spelling doaj-art-ba72c49811eb4a46bc09cdaabe7630d62025-08-20T03:14:20ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762025-05-01165149151https://doi.org/10.71152/ajms.v16i5.4493A rare case of angiosarcoma presenting as pleuro-pulmonary metastasis: A case reportAbi G 0https://orcid.org/0009-0000-4136-3009Pugazhendhi S 1https://orcid.org/0000-0002-2370-0726Padamati Advytha 2https://orcid.org/0009-0009-8254-2754Nalini Jayanthi Nagesh 3https://orcid.org/0000-0002-4672-0578Postgraduate Resident, Department of Respiratory Medicine, SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India Assistant Professor, Department of Respiratory Medicine, SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India Postgraduate Resident, Department of Respiratory Medicine, SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India Professor and Head, Department of Respiratory Medicine, SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India Angiosarcoma is an uncommon yet highly aggressive tumor originating from vascular endothelial cells, accounting for <2% of all sarcomas. Pulmonary involvement is often due to metastasis and presents with non-specific respiratory symptoms, leading to frequent misdiagnosis and delays in treatment. We report a case of a 74-year-old male with progressive breathlessness and recurrent hemoptysis. Imaging studies revealed multiple nodular deposits in the pleura and lung parenchyma. Histopathological and immunohistochemical analyses confirmed the diagnosis of metastatic angiosarcoma. This case underscores the significance of early recognition and histopathological confirmation in patients presenting with unexplained respiratory distress. A high index of suspicion is essential for timely diagnosis and intervention.https://ajmsjournal.info/index.php/AJMS/article/view/4493angiosarcoma; pulmonary metastasis; hemoptysis; pleural nodules; histopathology
spellingShingle Abi G
Pugazhendhi S
Padamati Advytha
Nalini Jayanthi Nagesh
A rare case of angiosarcoma presenting as pleuro-pulmonary metastasis: A case report
Asian Journal of Medical Sciences
angiosarcoma; pulmonary metastasis; hemoptysis; pleural nodules; histopathology
title A rare case of angiosarcoma presenting as pleuro-pulmonary metastasis: A case report
title_full A rare case of angiosarcoma presenting as pleuro-pulmonary metastasis: A case report
title_fullStr A rare case of angiosarcoma presenting as pleuro-pulmonary metastasis: A case report
title_full_unstemmed A rare case of angiosarcoma presenting as pleuro-pulmonary metastasis: A case report
title_short A rare case of angiosarcoma presenting as pleuro-pulmonary metastasis: A case report
title_sort rare case of angiosarcoma presenting as pleuro pulmonary metastasis a case report
topic angiosarcoma; pulmonary metastasis; hemoptysis; pleural nodules; histopathology
url https://ajmsjournal.info/index.php/AJMS/article/view/4493
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