Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus
Aim. To measure Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus (DM), elucidate its relationship with clinical manifestationsof the disease and biochemical blood characteristics. Materials and methods. A total of 76 DM patients were enrolled in this study (39 with DM1 and...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2009-06-01
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| Series: | Сахарный диабет |
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| Online Access: | https://www.dia-endojournals.ru/jour/article/view/5399 |
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| author | Z M Shamansurova F A Mukhamedova A G Tsoi A B Tashmanova A V Alieva N A Akhrarova |
| author_facet | Z M Shamansurova F A Mukhamedova A G Tsoi A B Tashmanova A V Alieva N A Akhrarova |
| author_sort | Z M Shamansurova |
| collection | DOAJ |
| description | Aim. To measure Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus (DM), elucidate its relationship with clinical manifestationsof the disease and biochemical blood characteristics. Materials and methods. A total of 76 DM patients were enrolled in this study (39 with DM1 and 35 with DM2). Control group consisted of 11 subjectswithout DM. They were examined for HbA1c, nitrite and nitrate levels in blood and membranes, sialidase activity in erythrocytes and Na-KATPaseactivity measured from variations of inorganic phosphorus content in the presence of ATP. Results. Na-K-ATPase activity in MD patients was significantly lower than in controls (p |
| format | Article |
| id | doaj-art-ba6ea2b9bd4a40ea96ecbed41c172bc2 |
| institution | OA Journals |
| issn | 2072-0351 2072-0378 |
| language | English |
| publishDate | 2009-06-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj-art-ba6ea2b9bd4a40ea96ecbed41c172bc22025-08-20T02:29:31ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782009-06-01122555710.14341/2072-0351-53995357Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitusZ M Shamansurova0F A Mukhamedova1A G Tsoi2A B Tashmanova3A V Alieva4N A Akhrarova5НИИ Эндокринологии МЗ РУз, ТашкентНИИ Эндокринологии МЗ РУз, ТашкентНИИ Эндокринологии МЗ РУз, ТашкентНИИ Эндокринологии МЗ РУз, ТашкентНИИ Эндокринологии МЗ РУз, ТашкентНИИ Эндокринологии МЗ РУз, ТашкентAim. To measure Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus (DM), elucidate its relationship with clinical manifestationsof the disease and biochemical blood characteristics. Materials and methods. A total of 76 DM patients were enrolled in this study (39 with DM1 and 35 with DM2). Control group consisted of 11 subjectswithout DM. They were examined for HbA1c, nitrite and nitrate levels in blood and membranes, sialidase activity in erythrocytes and Na-KATPaseactivity measured from variations of inorganic phosphorus content in the presence of ATP. Results. Na-K-ATPase activity in MD patients was significantly lower than in controls (phttps://www.dia-endojournals.ru/jour/article/view/5399na-k-atpaseelectrolyte gradient across plasma membranec peptidediabetic neuropathy |
| spellingShingle | Z M Shamansurova F A Mukhamedova A G Tsoi A B Tashmanova A V Alieva N A Akhrarova Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus Сахарный диабет na-k-atpase electrolyte gradient across plasma membrane c peptide diabetic neuropathy |
| title | Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus |
| title_full | Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus |
| title_fullStr | Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus |
| title_full_unstemmed | Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus |
| title_short | Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus |
| title_sort | abnormal na k atpase activity in erythrocytes from patients with diabetes mellitus |
| topic | na-k-atpase electrolyte gradient across plasma membrane c peptide diabetic neuropathy |
| url | https://www.dia-endojournals.ru/jour/article/view/5399 |
| work_keys_str_mv | AT zmshamansurova abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT famukhamedova abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT agtsoi abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT abtashmanova abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT avalieva abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus AT naakhrarova abnormalnakatpaseactivityinerythrocytesfrompatientswithdiabetesmellitus |