The practicality of interleukin-6 in prognosis of blunt chest trauma in Korea: a retrospective study
Purpose There are many studies on the practicality of interleukin-6 (IL-6) as a prognostic predictor in patients with multiple severe traumas. However, few studies focus on the practicality of IL-6 in patients with chest trauma. So, this study investigated whether IL-6 is effective as a prognostic f...
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| Format: | Article |
| Language: | English |
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Korean Society of Traumatology
2023-06-01
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| Series: | Journal of Trauma and Injury |
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| Online Access: | http://jtraumainj.org/upload/pdf/jti-2022-0050.pdf |
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| author | Jeong Woo Oh Tae Yeon Lee Minjeong Chae |
| author_facet | Jeong Woo Oh Tae Yeon Lee Minjeong Chae |
| author_sort | Jeong Woo Oh |
| collection | DOAJ |
| description | Purpose There are many studies on the practicality of interleukin-6 (IL-6) as a prognostic predictor in patients with multiple severe traumas. However, few studies focus on the practicality of IL-6 in patients with chest trauma. So, this study investigated whether IL-6 is effective as a prognostic factor in patients with blunt chest trauma. Methods A total of 44 blunt chest trauma patients who visited the regional trauma center from July to December 2021 were included in this retrospective study. Blood IL-6 levels were measured immediately after emergency room admittance (IL-6 E) and 24 hours after trauma (IL-6 24). To determine whether IL-6 levels can predict the clinical course and prognosis of patients with blunt chest trauma, the correlation between IL-6 (IL-6 E and IL-6 24) and the trauma score system, Injury Severity Score, Thoracic Trauma Severity Score, and Pulmonary Contusion Score, intensive care unit (ICU) stay period, and total hospitalization period were analyzed. Results IL-6 E showed a good correlation with Injury Severity Score (P=0.505), Thoracic Trauma Severity Score (P=0.597), Pulmonary Contusion Score (P=0.493), ICU stay period (P=0.762), and total hospitalization period (P=0.662). However, IL-6 24 had a relatively low correlation compared to IL-6 E. Therefore, IL-6 E showed useful results for predicting the prognosis of patients with blunt chest trauma. Conclusions Early plasma IL-6 levels (IL-6 E) can predict the injury severity of blunt chest trauma, length of ICU stay, and total hospitalization period. |
| format | Article |
| id | doaj-art-ba685d8c7813465a8beb664fe029dc04 |
| institution | Kabale University |
| issn | 2799-4317 2287-1683 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Korean Society of Traumatology |
| record_format | Article |
| series | Journal of Trauma and Injury |
| spelling | doaj-art-ba685d8c7813465a8beb664fe029dc042025-01-16T05:39:48ZengKorean Society of TraumatologyJournal of Trauma and Injury2799-43172287-16832023-06-0136211412010.20408/jti.2022.00501231The practicality of interleukin-6 in prognosis of blunt chest trauma in Korea: a retrospective studyJeong Woo Oh0Tae Yeon Lee1Minjeong Chae2 Department of Trauma Surgery, Trauma Center, Cheju Halla General Hospital, Jeju, Korea Department of Trauma Surgery, Trauma Center, Ulsan University Hospital, Ulsan, Korea Department of Nursing, Chosun Nursing College, Kwangju, KoreaPurpose There are many studies on the practicality of interleukin-6 (IL-6) as a prognostic predictor in patients with multiple severe traumas. However, few studies focus on the practicality of IL-6 in patients with chest trauma. So, this study investigated whether IL-6 is effective as a prognostic factor in patients with blunt chest trauma. Methods A total of 44 blunt chest trauma patients who visited the regional trauma center from July to December 2021 were included in this retrospective study. Blood IL-6 levels were measured immediately after emergency room admittance (IL-6 E) and 24 hours after trauma (IL-6 24). To determine whether IL-6 levels can predict the clinical course and prognosis of patients with blunt chest trauma, the correlation between IL-6 (IL-6 E and IL-6 24) and the trauma score system, Injury Severity Score, Thoracic Trauma Severity Score, and Pulmonary Contusion Score, intensive care unit (ICU) stay period, and total hospitalization period were analyzed. Results IL-6 E showed a good correlation with Injury Severity Score (P=0.505), Thoracic Trauma Severity Score (P=0.597), Pulmonary Contusion Score (P=0.493), ICU stay period (P=0.762), and total hospitalization period (P=0.662). However, IL-6 24 had a relatively low correlation compared to IL-6 E. Therefore, IL-6 E showed useful results for predicting the prognosis of patients with blunt chest trauma. Conclusions Early plasma IL-6 levels (IL-6 E) can predict the injury severity of blunt chest trauma, length of ICU stay, and total hospitalization period.http://jtraumainj.org/upload/pdf/jti-2022-0050.pdfinterleukin-6thoracic injuryinjury severity score |
| spellingShingle | Jeong Woo Oh Tae Yeon Lee Minjeong Chae The practicality of interleukin-6 in prognosis of blunt chest trauma in Korea: a retrospective study Journal of Trauma and Injury interleukin-6 thoracic injury injury severity score |
| title | The practicality of interleukin-6 in prognosis of blunt chest trauma in Korea: a retrospective study |
| title_full | The practicality of interleukin-6 in prognosis of blunt chest trauma in Korea: a retrospective study |
| title_fullStr | The practicality of interleukin-6 in prognosis of blunt chest trauma in Korea: a retrospective study |
| title_full_unstemmed | The practicality of interleukin-6 in prognosis of blunt chest trauma in Korea: a retrospective study |
| title_short | The practicality of interleukin-6 in prognosis of blunt chest trauma in Korea: a retrospective study |
| title_sort | practicality of interleukin 6 in prognosis of blunt chest trauma in korea a retrospective study |
| topic | interleukin-6 thoracic injury injury severity score |
| url | http://jtraumainj.org/upload/pdf/jti-2022-0050.pdf |
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