Identification of key genes as diagnostic biomarkers for IBD using bioinformatics and machine learning

Identification of key genes as diagnostic biomarkers for IBD using bioinformatics and machine learning

Abstract Background The pathogenesis of inflammatory bowel disease (IBD) involves complex molecular mechanisms, and achieving clinical remission remains challenging. This study aims to identify IBD-potential biomarkers, analyze their correlation with immune cell infiltration, and identify genes that...

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Bibliographic Details
Main Authors: Tianhao Li, Haoren Jing, Xinyu Gao, Te Zhang, Haitao Yao, Xipeng Zhang, Mingqing Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Inflammatory bowel disease
Diagnostic biomarker
Pathogenic mechanism
Bioinformatics
Mendelian randomization
Online Access:https://doi.org/10.1186/s12967-025-06531-1
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