ProFertil study protocol for the investigation of gonadotropin-releasing hormone agonists (GnRHa) during chemotherapy aiming at fertility protection of young women and teenagers with cancer in Sweden—a phase III randomised double-blinded placebo-controlled study

ProFertil study protocol for the investigation of gonadotropin-releasing hormone agonists (GnRHa) during chemotherapy aiming at fertility protection of young women and teenagers with cancer in Sweden—a phase III randomised double-blinded placebo-controlled study

Background Gonadotropin-releasing hormone agonists (GnRHa) cotreatment used to transiently suppress ovarian function during chemotherapy to prevent ovarian damage and preserve female fertility is used globally but efficacy is debated. Most clinical studies investigating a beneficial effect of GnRHa...

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Main Authors: Kenny A Rodriguez-Wallberg, Jonas Bergh, Antonis Valachis, Per Frisk, Theodoros Foukakis, Per Ljungman, Sandra Eloranta, Hanna Pauline Nilsson, Johan Malmros, Christina Linder Stragliotto, Erika Isaksson Friman, Barbro Linderholm, Anne Andersson, Sara Harrysson, Lovisa Vennström, Helena Mörse
Format: Article
Language:English
Published: BMJ Publishing Group 2023-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/12/e078023.full
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