Recent Advances in the Synthesis of Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-One and Benzo[<i>e</i>][1,3]Thiazin-4-One Derivatives
Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-one and benzo[<i>e</i>][1,3]thiazin-4-one derivatives, as significant sulfur- and nitrogen-containing heterocyclic compounds, are prevalent in natural products, pharmaceuticals, and food items. In recent years, a variety of i...
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MDPI AG
2025-05-01
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| Series: | Molecules |
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| author | Yongli He Dan Yuan Ke Yang Bindong Li |
| author_facet | Yongli He Dan Yuan Ke Yang Bindong Li |
| author_sort | Yongli He |
| collection | DOAJ |
| description | Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-one and benzo[<i>e</i>][1,3]thiazin-4-one derivatives, as significant sulfur- and nitrogen-containing heterocyclic compounds, are prevalent in natural products, pharmaceuticals, and food items. In recent years, a variety of innovative synthetic methodologies for these compounds have been developed. In this review, we will comprehensively introduce the major advances in the synthesis of benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-one and benzo[<i>e</i>][1,3]thiazin-4-one derivatives via both intramolecular and intermolecular pathways from 2012 to the present. |
| format | Article |
| id | doaj-art-ba55bb886b8d4964a412a9c0589303ce |
| institution | OA Journals |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj-art-ba55bb886b8d4964a412a9c0589303ce2025-08-20T01:56:41ZengMDPI AGMolecules1420-30492025-05-013010209910.3390/molecules30102099Recent Advances in the Synthesis of Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-One and Benzo[<i>e</i>][1,3]Thiazin-4-One DerivativesYongli He0Dan Yuan1Ke Yang2Bindong Li3School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, ChinaJiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, ChinaJiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, ChinaSchool of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, ChinaBenzo[<i>d</i>]isothiazol-3(2<i>H</i>)-one and benzo[<i>e</i>][1,3]thiazin-4-one derivatives, as significant sulfur- and nitrogen-containing heterocyclic compounds, are prevalent in natural products, pharmaceuticals, and food items. In recent years, a variety of innovative synthetic methodologies for these compounds have been developed. In this review, we will comprehensively introduce the major advances in the synthesis of benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-one and benzo[<i>e</i>][1,3]thiazin-4-one derivatives via both intramolecular and intermolecular pathways from 2012 to the present.https://www.mdpi.com/1420-3049/30/10/2099benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-onesbenzo[<i>e</i>][1,3]thiazin-4-onesorganic synthesis |
| spellingShingle | Yongli He Dan Yuan Ke Yang Bindong Li Recent Advances in the Synthesis of Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-One and Benzo[<i>e</i>][1,3]Thiazin-4-One Derivatives Molecules benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-ones benzo[<i>e</i>][1,3]thiazin-4-ones organic synthesis |
| title | Recent Advances in the Synthesis of Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-One and Benzo[<i>e</i>][1,3]Thiazin-4-One Derivatives |
| title_full | Recent Advances in the Synthesis of Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-One and Benzo[<i>e</i>][1,3]Thiazin-4-One Derivatives |
| title_fullStr | Recent Advances in the Synthesis of Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-One and Benzo[<i>e</i>][1,3]Thiazin-4-One Derivatives |
| title_full_unstemmed | Recent Advances in the Synthesis of Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-One and Benzo[<i>e</i>][1,3]Thiazin-4-One Derivatives |
| title_short | Recent Advances in the Synthesis of Benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-One and Benzo[<i>e</i>][1,3]Thiazin-4-One Derivatives |
| title_sort | recent advances in the synthesis of benzo i d i isothiazol 3 2 i h i one and benzo i e i 1 3 thiazin 4 one derivatives |
| topic | benzo[<i>d</i>]isothiazol-3(2<i>H</i>)-ones benzo[<i>e</i>][1,3]thiazin-4-ones organic synthesis |
| url | https://www.mdpi.com/1420-3049/30/10/2099 |
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