Impact of the COVID‐19 pandemic on the time to emergency endoscopy and clinical outcomes in patients with upper gastrointestinal bleeding

Abstract Objectives To investigate endoscopic management and clinical outcomes in patients with non‐variceal upper gastrointestinal (GI) bleeding during the coronavirus disease 2019 pandemic. Methods We retrospectively analyzed the data of 332 patients with non‐variceal upper GI bleeding who underwe...

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Main Authors: Takumi Komatsu, Yoshinori Sato, Yuichiro Kuroki, Yoshihito Yoshida, Natsumi Aoyama, Yoshihiko Iijima, Yusuke Nakamoto, Masaki Kato, Hirofumi Kiyokawa, Kenichiro Tanabe, Koutaro Matsunaga, Tadateru Maehata, Hiroshi Yasuda, Nobuyuki Matsumoto, Keisuke Tateishi
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:DEN Open
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Online Access:https://doi.org/10.1002/deo2.310
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author Takumi Komatsu
Yoshinori Sato
Yuichiro Kuroki
Yoshihito Yoshida
Natsumi Aoyama
Yoshihiko Iijima
Yusuke Nakamoto
Masaki Kato
Hirofumi Kiyokawa
Kenichiro Tanabe
Koutaro Matsunaga
Tadateru Maehata
Hiroshi Yasuda
Nobuyuki Matsumoto
Keisuke Tateishi
author_facet Takumi Komatsu
Yoshinori Sato
Yuichiro Kuroki
Yoshihito Yoshida
Natsumi Aoyama
Yoshihiko Iijima
Yusuke Nakamoto
Masaki Kato
Hirofumi Kiyokawa
Kenichiro Tanabe
Koutaro Matsunaga
Tadateru Maehata
Hiroshi Yasuda
Nobuyuki Matsumoto
Keisuke Tateishi
author_sort Takumi Komatsu
collection DOAJ
description Abstract Objectives To investigate endoscopic management and clinical outcomes in patients with non‐variceal upper gastrointestinal (GI) bleeding during the coronavirus disease 2019 pandemic. Methods We retrospectively analyzed the data of 332 patients with non‐variceal upper GI bleeding who underwent emergency upper GI endoscopy at three hospitals during the pandemic (April 2020–June 2021) and before the pandemic (January 2019–March 2020). The number of emergency upper GI endoscopies, time from hospital arrival to endoscopy, mortality within 30 days, rebleeding within 30 days, interventional radiology (IVR)/surgery requirement, composite outcome, rates of endoscopic hemostasis procedures, and second‐look endoscopy were investigated using logistic regression. Results Overall, 152 and 180 patients underwent emergency upper GI endoscopies during and before the pandemic, respectively. The mean time from arrival to endoscopy was longer during the pandemic than before it (11.7 vs. 6.1 h, p < 0.01). Multivariate analysis revealed that mortality within 30 days (odds ratio [OR]: 2.27, p = 0.26), rebleeding within 30 days (OR: 0.43, p = 0.17), IVR/surgery requirement (OR: 1.79, p = 0.33), and composite outcome (OR: 0.98, p = 0.96) did not differ significantly between the periods; conversely, endoscopic hemostasis procedures (OR: 0.38, p < 0.01) and second‐look endoscopies (OR: 0.04, p < 0.01) were less likely to be performed during the pandemic than before it. Conclusions Although the time from arrival to endoscopy was significantly longer during the pandemic, it did not affect mortality and rebleeding.
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spelling doaj-art-ba4b3afe9049411aa7eb6ffeca65b0622025-08-20T03:38:54ZengWileyDEN Open2692-46092024-04-0141n/an/a10.1002/deo2.310Impact of the COVID‐19 pandemic on the time to emergency endoscopy and clinical outcomes in patients with upper gastrointestinal bleedingTakumi Komatsu0Yoshinori Sato1Yuichiro Kuroki2Yoshihito Yoshida3Natsumi Aoyama4Yoshihiko Iijima5Yusuke Nakamoto6Masaki Kato7Hirofumi Kiyokawa8Kenichiro Tanabe9Koutaro Matsunaga10Tadateru Maehata11Hiroshi Yasuda12Nobuyuki Matsumoto13Keisuke Tateishi14Department of Gastroenterology St Marianna University School of Medicine Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine, Yokohama Seibu Hospital Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine, Yokohama Seibu Hospital Kanagawa JapanDepartment of Gastroenterology Kawasaki Municipal Tama Hospital Kanagawa JapanDepartment of Gastroenterology Kawasaki Municipal Tama Hospital Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine Kanagawa JapanPathophysiology and Bioregulation St. Marianna University Graduate School of Medicine Kanagawa JapanDepartment of Gastroenterology Kawasaki Municipal Tama Hospital Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine, Yokohama Seibu Hospital Kanagawa JapanDepartment of Gastroenterology St Marianna University School of Medicine Kanagawa JapanAbstract Objectives To investigate endoscopic management and clinical outcomes in patients with non‐variceal upper gastrointestinal (GI) bleeding during the coronavirus disease 2019 pandemic. Methods We retrospectively analyzed the data of 332 patients with non‐variceal upper GI bleeding who underwent emergency upper GI endoscopy at three hospitals during the pandemic (April 2020–June 2021) and before the pandemic (January 2019–March 2020). The number of emergency upper GI endoscopies, time from hospital arrival to endoscopy, mortality within 30 days, rebleeding within 30 days, interventional radiology (IVR)/surgery requirement, composite outcome, rates of endoscopic hemostasis procedures, and second‐look endoscopy were investigated using logistic regression. Results Overall, 152 and 180 patients underwent emergency upper GI endoscopies during and before the pandemic, respectively. The mean time from arrival to endoscopy was longer during the pandemic than before it (11.7 vs. 6.1 h, p < 0.01). Multivariate analysis revealed that mortality within 30 days (odds ratio [OR]: 2.27, p = 0.26), rebleeding within 30 days (OR: 0.43, p = 0.17), IVR/surgery requirement (OR: 1.79, p = 0.33), and composite outcome (OR: 0.98, p = 0.96) did not differ significantly between the periods; conversely, endoscopic hemostasis procedures (OR: 0.38, p < 0.01) and second‐look endoscopies (OR: 0.04, p < 0.01) were less likely to be performed during the pandemic than before it. Conclusions Although the time from arrival to endoscopy was significantly longer during the pandemic, it did not affect mortality and rebleeding.https://doi.org/10.1002/deo2.310COVID‐19emergenciesendoscopygastrointestinal hemorrhageretrospective studies
spellingShingle Takumi Komatsu
Yoshinori Sato
Yuichiro Kuroki
Yoshihito Yoshida
Natsumi Aoyama
Yoshihiko Iijima
Yusuke Nakamoto
Masaki Kato
Hirofumi Kiyokawa
Kenichiro Tanabe
Koutaro Matsunaga
Tadateru Maehata
Hiroshi Yasuda
Nobuyuki Matsumoto
Keisuke Tateishi
Impact of the COVID‐19 pandemic on the time to emergency endoscopy and clinical outcomes in patients with upper gastrointestinal bleeding
DEN Open
COVID‐19
emergencies
endoscopy
gastrointestinal hemorrhage
retrospective studies
title Impact of the COVID‐19 pandemic on the time to emergency endoscopy and clinical outcomes in patients with upper gastrointestinal bleeding
title_full Impact of the COVID‐19 pandemic on the time to emergency endoscopy and clinical outcomes in patients with upper gastrointestinal bleeding
title_fullStr Impact of the COVID‐19 pandemic on the time to emergency endoscopy and clinical outcomes in patients with upper gastrointestinal bleeding
title_full_unstemmed Impact of the COVID‐19 pandemic on the time to emergency endoscopy and clinical outcomes in patients with upper gastrointestinal bleeding
title_short Impact of the COVID‐19 pandemic on the time to emergency endoscopy and clinical outcomes in patients with upper gastrointestinal bleeding
title_sort impact of the covid 19 pandemic on the time to emergency endoscopy and clinical outcomes in patients with upper gastrointestinal bleeding
topic COVID‐19
emergencies
endoscopy
gastrointestinal hemorrhage
retrospective studies
url https://doi.org/10.1002/deo2.310
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