EfgA is a conserved formaldehyde sensor that leads to bacterial growth arrest in response to elevated formaldehyde.

EfgA is a conserved formaldehyde sensor that leads to bacterial growth arrest in response to elevated formaldehyde.

Normal cellular processes give rise to toxic metabolites that cells must mitigate. Formaldehyde is a universal stressor and potent metabolic toxin that is generated in organisms from bacteria to humans. Methylotrophic bacteria such as Methylorubrum extorquens face an acute challenge due to their pro...

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Bibliographic Details
Main Authors: Jannell V Bazurto, Dipti D Nayak, Tomislav Ticak, Milya Davlieva, Jessica A Lee, Chandler N Hellenbrand, Leah B Lambert, Olivia J Benski, Caleb J Quates, Jill L Johnson, Jagdish Suresh Patel, F Marty Ytreberg, Yousif Shamoo, Christopher J Marx
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001208&type=printable
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