Clinical analysis of left renal veIn cntrapment syndrome complicated with IgA nephropathy
Objective To improve the ability of clinicians in diagnosis of left renal velncntrapment syndrome complicated with IgA nephropathy through analyzing the clinical data of patients.Methods Clinical data of six cases of left renal velncntrapment syndrome complicated with IgA nephropathy were analyzed r...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2015-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57920912&Fpath=home&index=0 |
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| Summary: | Objective To improve the ability of clinicians in diagnosis of left renal velncntrapment syndrome complicated with IgA nephropathy through analyzing the clinical data of patients.Methods Clinical data of six cases of left renal velncntrapment syndrome complicated with IgA nephropathy were analyzed retrospectively.Left renal velncntrapment syndrome was diagnosed by Doppler sonography and one case was also by computed tomography angiography（CTA）.IgA nephropathy was diagnosed by renal biopsy.The clinical data,including age,sex,height,body mass,urinary protein,blood routine,serum creatinine（SCr）,albumin（Alb）,serum uric acid,complement C3,renal pathologic category and images,were analyzed in all 6 patients.Results All 6 patients were male with a mean age of（16.5 ± 4.3） years old.The body mass index（BMI） was 17.8 ± 1.3.Clinical presentation included proteinuria,haematuria and loin pain.Pathologic evaluation revealed Lee Ⅰ<sup>L</sup>ee Ⅲ IgA nephropathy;one patient was Lee Ⅰ,four patients were Lee Ⅱ,one patient was Lee Ⅲ;One patient had cellular crescent（5.9%of total glomerular）,one patients had glomerular sclerosis（14.3%of total glomerular）.All 6 patientsexhibited mild to moderate mesangialhypercellularity,mild tubular atrophy,and mild tubular fibrosis,All 6 patients had no interstitial vasculitis;two patients had focal interstitial inflammation.In immunohistochemistry;all 6 patients showed dominant positive staining for IgA（++ <sup> </sup>+++）,IgG（++）,and C3（+ <sup>+</sup>+） in the mesangium,IgM was not found in all patients.Conclusions Supine/standing urinalysis combined with Doppler sonography should be considered in patients who are adolescents with low BMI manifesting intermittent proteinuria and/or haematuria,which can be helpful for differential diagnosis and treatment to avoid over-treatment. |
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| ISSN: | 1671-2390 |