Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis

Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis

BackgroundTanshinone ⅡA (Tan ⅡA) is a monomer extracted from Salvia miltiorrhiza Bunge. Animal studies have demonstrated its potential in providing cognitive protection in Alzheimer’s disease (AD), but the overall effects remain inconclusive, and its multiple mechanisms have not been systematically...

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Bibliographic Details
Main Authors:	Yuanhang Rong, Qinqing Li, Yuzhong Du, Wenting Wang, Wenna Su, Junlong Zhang, Wenbin He
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Pharmacology
Subjects:	Alzheimer’s disease animal models cognitive function mechanisms systematic review and meta-analysis Tanshinone ⅡA
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1603861/full
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